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Extending pummerer reaction chemistry. Synthesis studies in the phakellin alkaloid area

  • Ken S. Feldman
  • , Amanda P. Skoumbourdis
  • , Matthew D. Fodor

Research output: Contribution to journalArticlepeer-review

Abstract

(Chemical Equation Presented) The syntheses of (±)- dibromophakellstatin and, from this species, (±)-dibromophakellin are described. Oxidative cyclization of a phenylthiolated dihydrooroidin derivative triggered by a Pummerer reaction constitutes the key step in this biomimetic approach to this family of marine alkaloids.

Original languageEnglish (US)
Pages (from-to)8076-8086
Number of pages11
JournalJournal of Organic Chemistry
Volume72
Issue number21
DOIs
StatePublished - Oct 12 2007

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 14 - Life Below Water
    SDG 14 Life Below Water

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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