External Validation of the COVID-NoLab and COVID-SimpleLab Prognostic Tools

Mark H. Ebell; Robert P. Lennon; Derjung M. Tarn; Bruce Barrett; Alex H. Krist; Huamei Dong; Xinyan Cai; Arch G. Mainous; Aleksandra E. Zgierska; Wen Jan Tuan; Munish Goyal

doi:10.1370/afm.2872

External Validation of the COVID-NoLab and COVID-SimpleLab Prognostic Tools

Mark H. Ebell
, Robert P. Lennon
, Derjung M. Tarn
, Bruce Barrett
, Alex H. Krist
, Huamei Dong
, Xinyan Cai
, Arch G. Mainous
, Aleksandra E. Zgierska
, Wen Jan Tuan
, Munish Goyal

Research output: Contribution to journal › Article › peer-review

Abstract

Our objective was to externally validate 2 simple risk scores for mortality among a mostly inpatient population with COVID-19 in Canada (588 patients for COVID-NoLab and 479 patients for COVID-SimpleLab). The mortality rates in the low-, moderate-, and high-risk groups for COVID-NoLab were 1.1%, 9.6%, and 21.2%, respectively. The mortality rates for COVID-SimpleLab were 0.0%, 9.8%, and 20.0%, respectively. These values were similar to those in the original derivation cohort. The 2 simple risk scores, now successfully externally validated, offer clinicians a reliable way to quickly identify low-risk inpatients who could potentially be managed as outpatients in the event of a bed shortage. Both are avail-able online (https://ebell-projects.shinyapps.io/covid_nolab/ and https://ebell-projects.shiny apps.io/COVID-SimpleLab/).

Original language	English (US)
Pages (from-to)	548-550
Number of pages	3
Journal	Annals of family medicine
Volume	20
Issue number	6
DOIs	https://doi.org/10.1370/afm.2872
State	Published - Nov 1 2022

All Science Journal Classification (ASJC) codes

Family Practice

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10.1370/afm.2872

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@article{c4c359ee503041d29434acd0740a920c,

title = "External Validation of the COVID-NoLab and COVID-SimpleLab Prognostic Tools",

abstract = "Our objective was to externally validate 2 simple risk scores for mortality among a mostly inpatient population with COVID-19 in Canada (588 patients for COVID-NoLab and 479 patients for COVID-SimpleLab). The mortality rates in the low-, moderate-, and high-risk groups for COVID-NoLab were 1.1\%, 9.6\%, and 21.2\%, respectively. The mortality rates for COVID-SimpleLab were 0.0\%, 9.8\%, and 20.0\%, respectively. These values were similar to those in the original derivation cohort. The 2 simple risk scores, now successfully externally validated, offer clinicians a reliable way to quickly identify low-risk inpatients who could potentially be managed as outpatients in the event of a bed shortage. Both are avail-able online (https://ebell-projects.shinyapps.io/covid\_nolab/ and https://ebell-projects.shiny apps.io/COVID-SimpleLab/).",

author = "Ebell, \{Mark H.\} and Lennon, \{Robert P.\} and Tarn, \{Derjung M.\} and Bruce Barrett and Krist, \{Alex H.\} and Huamei Dong and Xinyan Cai and Mainous, \{Arch G.\} and Zgierska, \{Aleksandra E.\} and Tuan, \{Wen Jan\} and Munish Goyal",

year = "2022",

month = nov,

day = "1",

doi = "10.1370/afm.2872",

language = "English (US)",

volume = "20",

pages = "548--550",

journal = "Annals of family medicine",

issn = "1544-1709",

publisher = "Annals of Family Medicine, Inc",

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TY - JOUR

T1 - External Validation of the COVID-NoLab and COVID-SimpleLab Prognostic Tools

AU - Ebell, Mark H.

AU - Lennon, Robert P.

AU - Tarn, Derjung M.

AU - Barrett, Bruce

AU - Krist, Alex H.

AU - Dong, Huamei

AU - Cai, Xinyan

AU - Mainous, Arch G.

AU - Zgierska, Aleksandra E.

AU - Tuan, Wen Jan

AU - Goyal, Munish

PY - 2022/11/1

Y1 - 2022/11/1

N2 - Our objective was to externally validate 2 simple risk scores for mortality among a mostly inpatient population with COVID-19 in Canada (588 patients for COVID-NoLab and 479 patients for COVID-SimpleLab). The mortality rates in the low-, moderate-, and high-risk groups for COVID-NoLab were 1.1%, 9.6%, and 21.2%, respectively. The mortality rates for COVID-SimpleLab were 0.0%, 9.8%, and 20.0%, respectively. These values were similar to those in the original derivation cohort. The 2 simple risk scores, now successfully externally validated, offer clinicians a reliable way to quickly identify low-risk inpatients who could potentially be managed as outpatients in the event of a bed shortage. Both are avail-able online (https://ebell-projects.shinyapps.io/covid_nolab/ and https://ebell-projects.shiny apps.io/COVID-SimpleLab/).

AB - Our objective was to externally validate 2 simple risk scores for mortality among a mostly inpatient population with COVID-19 in Canada (588 patients for COVID-NoLab and 479 patients for COVID-SimpleLab). The mortality rates in the low-, moderate-, and high-risk groups for COVID-NoLab were 1.1%, 9.6%, and 21.2%, respectively. The mortality rates for COVID-SimpleLab were 0.0%, 9.8%, and 20.0%, respectively. These values were similar to those in the original derivation cohort. The 2 simple risk scores, now successfully externally validated, offer clinicians a reliable way to quickly identify low-risk inpatients who could potentially be managed as outpatients in the event of a bed shortage. Both are avail-able online (https://ebell-projects.shinyapps.io/covid_nolab/ and https://ebell-projects.shiny apps.io/COVID-SimpleLab/).

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UR - https://www.scopus.com/pages/publications/85142616776#tab=citedBy

U2 - 10.1370/afm.2872

DO - 10.1370/afm.2872

M3 - Article

C2 - 36443081

AN - SCOPUS:85142616776

SN - 1544-1709

VL - 20

SP - 548

EP - 550

JO - Annals of family medicine

JF - Annals of family medicine

IS - 6

ER -

External Validation of the COVID-NoLab and COVID-SimpleLab Prognostic Tools

Abstract

All Science Journal Classification (ASJC) codes

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