False-positive lesions mimicking breast cancer on FDG PET and PET/CT

Margaret Adejolu; Lei Huo; Eric Rohren; Lumarie Santiago; Wei T. Yang

doi:10.2214/AJR.11.7130

False-positive lesions mimicking breast cancer on FDG PET and PET/CT

Margaret Adejolu
, Lei Huo
, Eric Rohren
, Lumarie Santiago
, Wei T. Yang

Department of Radiology

Research output: Contribution to journal › Review article › peer-review

114 Scopus citations

Abstract

OBJECTIVE. Incidental ¹⁸F-FDG-avid breast lesions are commonly encountered in patients with cancer who undergo staging PET/CT. This pictorial essay discusses breast lesions that show increased FDG activity, mimicking breast cancer, with biopsy-confirmed benign diagnosis. CONCLUSION. Acute and chronic inflammation, physiologic lactation, and benign breast masses, including silicone granuloma, fat necrosis, fibroadenoma, and postsurgical changes, may show increased FDG uptake on PET/CT. These conditions can often be differentiated from malignancy by correlative imaging, including mammography, sonography, or MRI.

Original language	English (US)
Pages (from-to)	W304-W314
Journal	American Journal of Roentgenology
Volume	198
Issue number	3
DOIs	https://doi.org/10.2214/AJR.11.7130
State	Published - Mar 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Radiology Nuclear Medicine and imaging

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10.2214/AJR.11.7130

Cite this

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title = "False-positive lesions mimicking breast cancer on FDG PET and PET/CT",

abstract = "OBJECTIVE. Incidental 18F-FDG-avid breast lesions are commonly encountered in patients with cancer who undergo staging PET/CT. This pictorial essay discusses breast lesions that show increased FDG activity, mimicking breast cancer, with biopsy-confirmed benign diagnosis. CONCLUSION. Acute and chronic inflammation, physiologic lactation, and benign breast masses, including silicone granuloma, fat necrosis, fibroadenoma, and postsurgical changes, may show increased FDG uptake on PET/CT. These conditions can often be differentiated from malignancy by correlative imaging, including mammography, sonography, or MRI.",

author = "Margaret Adejolu and Lei Huo and Eric Rohren and Lumarie Santiago and Yang, \{Wei T.\}",

year = "2012",

month = mar,

doi = "10.2214/AJR.11.7130",

language = "English (US)",

volume = "198",

pages = "W304--W314",

journal = "American Journal of Roentgenology",

issn = "0361-803X",

publisher = "American Roentgen Ray Society",

number = "3",

}

TY - JOUR

T1 - False-positive lesions mimicking breast cancer on FDG PET and PET/CT

AU - Adejolu, Margaret

AU - Huo, Lei

AU - Rohren, Eric

AU - Santiago, Lumarie

AU - Yang, Wei T.

PY - 2012/3

Y1 - 2012/3

N2 - OBJECTIVE. Incidental 18F-FDG-avid breast lesions are commonly encountered in patients with cancer who undergo staging PET/CT. This pictorial essay discusses breast lesions that show increased FDG activity, mimicking breast cancer, with biopsy-confirmed benign diagnosis. CONCLUSION. Acute and chronic inflammation, physiologic lactation, and benign breast masses, including silicone granuloma, fat necrosis, fibroadenoma, and postsurgical changes, may show increased FDG uptake on PET/CT. These conditions can often be differentiated from malignancy by correlative imaging, including mammography, sonography, or MRI.

AB - OBJECTIVE. Incidental 18F-FDG-avid breast lesions are commonly encountered in patients with cancer who undergo staging PET/CT. This pictorial essay discusses breast lesions that show increased FDG activity, mimicking breast cancer, with biopsy-confirmed benign diagnosis. CONCLUSION. Acute and chronic inflammation, physiologic lactation, and benign breast masses, including silicone granuloma, fat necrosis, fibroadenoma, and postsurgical changes, may show increased FDG uptake on PET/CT. These conditions can often be differentiated from malignancy by correlative imaging, including mammography, sonography, or MRI.

UR - https://www.scopus.com/pages/publications/84863274620

UR - https://www.scopus.com/pages/publications/84863274620#tab=citedBy

U2 - 10.2214/AJR.11.7130

DO - 10.2214/AJR.11.7130

M3 - Review article

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AN - SCOPUS:84863274620

SN - 0361-803X

VL - 198

SP - W304-W314

JO - American Journal of Roentgenology

JF - American Journal of Roentgenology

IS - 3

ER -

False-positive lesions mimicking breast cancer on FDG PET and PET/CT

Abstract

UN SDGs

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