TY - JOUR
T1 - Feasibility of miniature high-frequency piezoelectric ceramic hollow spheres for exposimetry and tissue ablation
AU - Al-Bataineh, Osama M.
AU - Markley, Douglas C.
AU - Meyer, Richard J.
AU - Newnham, Robert E.
AU - Smith, Nadine Barrie
PY - 2004/6
Y1 - 2004/6
N2 - Miniature, high frequency piezoelectric ceramic hollow spheres were evaluated for potential use as hydrophones for exposimetry of high intensity ultrasound fields and as minimally invasive tissue ablation devices. Spheres with diameters ranging from 0.7 to 1.0 mm, with resonance frequencies from 1.8 to 2.7 MHz were used as hydrophones. An almost constant sensitivity was reported for these hydrophones and an omni directional receive pattern was also demonstrated. The hollow sphere hydrophone exhibited twice the sensitivity of a needle hydrophone but with no pre-amplification stages and could withstand four times higher pressure. As a minimally invasive interstitial ablation device, the results demonstrated an increased necrosed tissue volume for increasing exposure time. For example, with a 1.0 mm diameter sphere (f = 1.87 MHz), the necrosed tissue diameter as a function of exposure times was 2.35 ± 0.34, 3.00 ± 0.37 and 4.61 ± 1.13 mm for 5, 10 and 15 sec. sonications, respectively.
AB - Miniature, high frequency piezoelectric ceramic hollow spheres were evaluated for potential use as hydrophones for exposimetry of high intensity ultrasound fields and as minimally invasive tissue ablation devices. Spheres with diameters ranging from 0.7 to 1.0 mm, with resonance frequencies from 1.8 to 2.7 MHz were used as hydrophones. An almost constant sensitivity was reported for these hydrophones and an omni directional receive pattern was also demonstrated. The hollow sphere hydrophone exhibited twice the sensitivity of a needle hydrophone but with no pre-amplification stages and could withstand four times higher pressure. As a minimally invasive interstitial ablation device, the results demonstrated an increased necrosed tissue volume for increasing exposure time. For example, with a 1.0 mm diameter sphere (f = 1.87 MHz), the necrosed tissue diameter as a function of exposure times was 2.35 ± 0.34, 3.00 ± 0.37 and 4.61 ± 1.13 mm for 5, 10 and 15 sec. sonications, respectively.
UR - http://www.scopus.com/inward/record.url?scp=3142693604&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=3142693604&partnerID=8YFLogxK
U2 - 10.1080/14328917.2004.11784834
DO - 10.1080/14328917.2004.11784834
M3 - Article
AN - SCOPUS:3142693604
SN - 1432-8917
VL - 8
SP - 78
EP - 83
JO - Materials Research Innovations
JF - Materials Research Innovations
IS - 2
ER -