Abstract
A 34-year-old female with left-sided ulcerative colitis (UC) developed severe febrile neutropenia/thrombocytopenia soon after infliximab induction therapy. There was no other plausible cause of the cell line abnormalities other than an accurate temporal association with infliximab administration. Supportive care, broad-spectrum antibiotic, and single dose of filgrastim was given on day 5 of admission due to persistently low absolute neutrophil count and fevers. The cell lines recovered, fever resolved and the patient made a complete clinical recovery. Clinicians should be aware of this potential life-threatening inflixmab side effect previously unreported in adults with UC.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 596-599 |
| Number of pages | 4 |
| Journal | Case Reports in Gastroenterology |
| Volume | 10 |
| Issue number | 3 |
| DOIs | |
| State | Published - Oct 6 2016 |
All Science Journal Classification (ASJC) codes
- Gastroenterology
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