TY - JOUR
T1 - Fertility patients' views about frozen embryo disposition
T2 - results of a multi-institutional U.S. survey
AU - Lyerly, Anne Drapkin
AU - Steinhauser, Karen
AU - Voils, Corrine
AU - Namey, Emily
AU - Alexander, Carolyn
AU - Bankowski, Brandon
AU - Cook-Deegan, Robert
AU - Dodson, William C.
AU - Gates, Elena
AU - Jungheim, Emily S.
AU - McGovern, Peter G.
AU - Myers, Evan R.
AU - Osborn, Barbara
AU - Schlaff, William
AU - Sugarman, Jeremy
AU - Tulsky, James A.
AU - Walmer, David
AU - Faden, Ruth R.
AU - Wallach, Edward
PY - 2010/1/15
Y1 - 2010/1/15
N2 - Objective: To describe fertility patients' preferences for disposition of cryopreserved embryos and determine factors important to these preferences. Design: Cross-sectional survey conducted between June 2006 and July 2007. Setting: Nine geographically diverse U.S. fertility clinics. Patient(s): 1020 fertility patients with cryopreserved embryos. Intervention(s): Self-administered questionnaire. Main Outcome Measure(s): Likelihood of selecting each of five conventional embryo disposition options: store for reproduction, thaw and discard, donate to another couple, freeze indefinitely, and donate for research; likelihood of selecting each of two alternative options identified in previous research: placement of embryos in the woman's body at an infertile time, or a disposal ceremony; importance of each of 26 considerations to disposition decisions; and views on the embryo's moral status. Result(s): We found that 54% of respondents with cryopreserved embryos were very likely to use them for reproduction, 21% were very likely to donate for research, 7% or fewer were very likely to choose any other option. Respondents who ascribed high importance to concerns about the health or well-being of the embryo, fetus, or future child were more likely to thaw and discard embryos or freeze them indefinitely. Conclusion(s): Fertility patients frequently prefer disposition options that are not available to them or find the available options unacceptable. Restructuring and standardizing the informed consent process and ensuring availability of all disposition options may benefit patients, facilitate disposition decisions, and address problems of long-term storage.
AB - Objective: To describe fertility patients' preferences for disposition of cryopreserved embryos and determine factors important to these preferences. Design: Cross-sectional survey conducted between June 2006 and July 2007. Setting: Nine geographically diverse U.S. fertility clinics. Patient(s): 1020 fertility patients with cryopreserved embryos. Intervention(s): Self-administered questionnaire. Main Outcome Measure(s): Likelihood of selecting each of five conventional embryo disposition options: store for reproduction, thaw and discard, donate to another couple, freeze indefinitely, and donate for research; likelihood of selecting each of two alternative options identified in previous research: placement of embryos in the woman's body at an infertile time, or a disposal ceremony; importance of each of 26 considerations to disposition decisions; and views on the embryo's moral status. Result(s): We found that 54% of respondents with cryopreserved embryos were very likely to use them for reproduction, 21% were very likely to donate for research, 7% or fewer were very likely to choose any other option. Respondents who ascribed high importance to concerns about the health or well-being of the embryo, fetus, or future child were more likely to thaw and discard embryos or freeze them indefinitely. Conclusion(s): Fertility patients frequently prefer disposition options that are not available to them or find the available options unacceptable. Restructuring and standardizing the informed consent process and ensuring availability of all disposition options may benefit patients, facilitate disposition decisions, and address problems of long-term storage.
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U2 - 10.1016/j.fertnstert.2008.10.015
DO - 10.1016/j.fertnstert.2008.10.015
M3 - Article
C2 - 19061998
AN - SCOPUS:74449085018
SN - 0015-0282
VL - 93
SP - 499
EP - 509
JO - Fertility and sterility
JF - Fertility and sterility
IS - 2
ER -