First in-human clinical performance of a new non-cavitating handheld lensectomy system in 665 consecutive cataract surgeries

Tsontcho Ianchulev, Elizabeth Yeu, Edward H. Hu, Paul Singh, Gautam Kamthan, Gavin Li, Seth Pantanelli, Farrell Tyson

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose:To investigate the intraoperative performance and lens fragmentation efficacy of a non-cavitating handheld lensectomy system in mild, moderate, and severe cataract.Setting:Ambulatory surgical centers.Design:Retrospective consecutive case series.Methods:665 consecutive eyes underwent cataract surgery by 12 surgeons using a new handheld non-cavitating lensectomy system for nuclear fragmentations and extraction. Intraoperative measurements included surgical time, miLOOP pretreatment, and irrigation fluid use.Results:Of the 665 eyes, 38 (6%), 468 (70%), 126 (19%), and 33 (5%) were of grade 1, 2, 3, and 4 nuclear densities, respectively, as graded by the surgeon intraoperatively. Successful nuclear fragmentation, lens extraction, and cortical removal were achieved in all eyes. Total nucleus fragmentation and extraction times were 70.1 seconds, 100.3 seconds, 132.6 seconds, and 287.9 seconds for grades 1, 2, 3, and 4, respectively (P <.001). In addition, irrigation and aspiration cortical removal times were 64.1 seconds, 51.1 seconds, 48.5 seconds, and 59.0 seconds, respectively (P =.14). There was a low rate of capsular tear (3 cases in 665 surgeries, 0.45%) and no other emergent adverse events.Conclusions:The miCOR handheld non-cavitating lensectomy system demonstrated nuclear fragmentation and extraction in the absence of intraocular cavitation across all grades of nuclear densities.

Original languageEnglish (US)
Pages (from-to)693-697
Number of pages5
JournalJournal of Cataract and Refractive Surgery
Volume50
Issue number7
DOIs
StatePublished - Jul 1 2024

All Science Journal Classification (ASJC) codes

  • General Medicine

Fingerprint

Dive into the research topics of 'First in-human clinical performance of a new non-cavitating handheld lensectomy system in 665 consecutive cataract surgeries'. Together they form a unique fingerprint.

Cite this