First synthesis of 2-aminopyrrole and simple 1-substituted-2-aminopyrroles. Observation of fast proton exchange at C-5.

Michael De Rosa, Roy P. Issac, Gregory Houghton

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

N-(1-substituent-111-pyrrol-2-yl)phlhalimides can be used to prepare the previously unknown 2-aminopyrrole and 1-substituted 2-aminopyrroles which undergo fast proton exchange at C-5 in acetic acid at 25 °C.

Original languageEnglish (US)
Pages (from-to)9261-9264
Number of pages4
JournalTetrahedron Letters
Volume36
Issue number51
DOIs
StatePublished - Dec 18 1995

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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