First synthesis of 2-aminopyrrole and simple 1-substituted-2-aminopyrroles. Observation of fast proton exchange at C-5.

Michael De Rosa; Roy P. Issac; Gregory Houghton

doi:10.1016/0040-4039(95)02019-L

First synthesis of 2-aminopyrrole and simple 1-substituted-2-aminopyrroles. Observation of fast proton exchange at C-5.

Michael De Rosa, Roy P. Issac, Gregory Houghton

Penn State Brandywine

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

N-(1-substituent-111-pyrrol-2-yl)phlhalimides can be used to prepare the previously unknown 2-aminopyrrole and 1-substituted 2-aminopyrroles which undergo fast proton exchange at C-5 in acetic acid at 25 °C.

Original language	English (US)
Pages (from-to)	9261-9264
Number of pages	4
Journal	Tetrahedron Letters
Volume	36
Issue number	51
DOIs	https://doi.org/10.1016/0040-4039(95)02019-L
State	Published - Dec 18 1995

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/0040-4039(95)02019-L

Cite this

@article{d20bd459cdfd4159b854b355e241756b,

title = "First synthesis of 2-aminopyrrole and simple 1-substituted-2-aminopyrroles. Observation of fast proton exchange at C-5.",

abstract = "N-(1-substituent-111-pyrrol-2-yl)phlhalimides can be used to prepare the previously unknown 2-aminopyrrole and 1-substituted 2-aminopyrroles which undergo fast proton exchange at C-5 in acetic acid at 25 °C.",

author = "Rosa, \{Michael De\} and Issac, \{Roy P.\} and Gregory Houghton",

note = "Funding Information: Acknowledgment: This work was funded through grants CHE 9007784 and CHE 9420655 from the National Science Foundation. High field tH nmr spectra were courtesy of Prof. Mark Timken, Widener University.",

year = "1995",

month = dec,

day = "18",

doi = "10.1016/0040-4039(95)02019-L",

language = "English (US)",

volume = "36",

pages = "9261--9264",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd",

number = "51",

}

TY - JOUR

T1 - First synthesis of 2-aminopyrrole and simple 1-substituted-2-aminopyrroles. Observation of fast proton exchange at C-5.

AU - Rosa, Michael De

AU - Issac, Roy P.

AU - Houghton, Gregory

N1 - Funding Information: Acknowledgment: This work was funded through grants CHE 9007784 and CHE 9420655 from the National Science Foundation. High field tH nmr spectra were courtesy of Prof. Mark Timken, Widener University.

PY - 1995/12/18

Y1 - 1995/12/18

N2 - N-(1-substituent-111-pyrrol-2-yl)phlhalimides can be used to prepare the previously unknown 2-aminopyrrole and 1-substituted 2-aminopyrroles which undergo fast proton exchange at C-5 in acetic acid at 25 °C.

AB - N-(1-substituent-111-pyrrol-2-yl)phlhalimides can be used to prepare the previously unknown 2-aminopyrrole and 1-substituted 2-aminopyrroles which undergo fast proton exchange at C-5 in acetic acid at 25 °C.

UR - https://www.scopus.com/pages/publications/0028843774

UR - https://www.scopus.com/inward/citedby.url?scp=0028843774&partnerID=8YFLogxK

U2 - 10.1016/0040-4039(95)02019-L

DO - 10.1016/0040-4039(95)02019-L

M3 - Article

AN - SCOPUS:0028843774

SN - 0040-4039

VL - 36

SP - 9261

EP - 9264

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 51

ER -

First synthesis of 2-aminopyrrole and simple 1-substituted-2-aminopyrroles. Observation of fast proton exchange at C-5.

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this