Abstract
This article describes FLASH (Fast Lithographic Activation of Sheets), a rapid method for laboratory prototyping of microfluidic devices in paper. Paper-based microfluidic devices are emerging as a new technology for applications in diagnostics for the developing world, where low cost and simplicity are essential. FLASH is based on photolithography, but requires only a UV lamp and a hotplate; no clean-room or special facilities are required (FLASH patterning can even be performed in sunlight if a UV lamp and hotplate are unavailable). The method provides channels in paper with dimensions as small as 200 μm in width and 70 μm in height; the height is defined by the thickness of the paper. Photomasks for patterning paper-based microfluidic devices can be printed using an ink-jet printer or photocopier, or drawn by hand using a waterproof black pen. FLASH provides a straightforward method for prototyping paper-based microfluidic devices in regions where the technological support for conventional photolithography is not available.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2146-2150 |
| Number of pages | 5 |
| Journal | Lab on a Chip |
| Volume | 8 |
| Issue number | 12 |
| DOIs | |
| State | Published - 2008 |
All Science Journal Classification (ASJC) codes
- Bioengineering
- Biochemistry
- General Chemistry
- Biomedical Engineering