Flexibility, diversity, and cooperativity: Pillars of enzyme catalysis

Keyphrases

• Aspartate Aminotransferase 33%
• Collective Response 33%
• Conformational Change 66%
• Cooperativity 100%
• Enzyme Mechanism 33%
• Enzyme-catalyzed 100%
• Enzyme-substrate Complex 33%
• Fast Reactions 33%
• Fluorescence Method 33%
• Free Energy Surface 33%
• General Mechanism 33%
• Historical Development 33%
• Hydride Transfer 33%
• Methylenetetrahydrofolate Reductase (MTHFR) 66%
• Nuclear Magnetic Resonance 33%
• Protein Conformation 33%
• Protein Flexibility 33%
• Reaction Coordinate 33%
• Reaction Method 33%
• Ribonuclease 33%
• Single-molecule Fluorescence 33%
• Standard Free Energy 33%
• Steady-state Kinetics 33%

Chemistry

• Aspartate 33%
• Aspartic Acid 33%
• Catalysis 100%
• Chemical Kinetics Characteristics 33%
• Dihydrofolates 66%
• NMR Spectroscopy 33%
• Protein Conformation 33%
• Single-Molecule Fluorescence 33%
• Surface Free Energy 33%