TY - GEN
T1 - Fluid dynamics of valve closure and sustained regurgitation in cardiac valve prostheses
AU - Bachmann, C.
AU - Deutsch, S.
AU - Fontaine, A.
AU - Tarbell, J. M.
PY - 1999/12/1
Y1 - 1999/12/1
N2 - It is believed that the fluid mechanical stresses associated with valve closure and sustained regurgitation are responsible for a significant portion of the blood damage observed with the use of mechanical cardiac valve replacements. The high velocity spikes and extreme pressure fluctuations associated with the impact of the occluder and the housing have been suspect in the initiation of cavitation, which can lead to increased hemolysis, excessive valve damage, and the formation of stable bubbles. These events have been photographed in vitro, and there is evidence of their occurrence in vivo. The fluid dynamic events at the instant of valve closure have not yet been captured experimentally. Two dimensional Laser Doppler Velocimetry was used to investigate the fluid dynamic aspects associated with valve closure and sustained regurgitation in vitro on artificial heart valves in the mitral position.
AB - It is believed that the fluid mechanical stresses associated with valve closure and sustained regurgitation are responsible for a significant portion of the blood damage observed with the use of mechanical cardiac valve replacements. The high velocity spikes and extreme pressure fluctuations associated with the impact of the occluder and the housing have been suspect in the initiation of cavitation, which can lead to increased hemolysis, excessive valve damage, and the formation of stable bubbles. These events have been photographed in vitro, and there is evidence of their occurrence in vivo. The fluid dynamic events at the instant of valve closure have not yet been captured experimentally. Two dimensional Laser Doppler Velocimetry was used to investigate the fluid dynamic aspects associated with valve closure and sustained regurgitation in vitro on artificial heart valves in the mitral position.
UR - https://www.scopus.com/pages/publications/0033323335
UR - https://www.scopus.com/inward/citedby.url?scp=0033323335&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:0033323335
SN - 0780356756
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
BT - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
PB - IEEE
T2 - Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
Y2 - 13 October 1999 through 16 October 1999
ER -