Fluid management in children with volume depletion

Jakub Zieg, Deepti Narla, Lucie Gonsorcikova, Rupesh Raina

Research output: Contribution to journalReview articlepeer-review


Volume depletion is a common condition and a frequent cause of hospitalization in children. Proper assessment of the patient includes a detailed history and a thorough physical examination. Biochemical tests may be useful in selected cases. Understanding the pathophysiology of fluid balance is necessary for appropriate management. A clinical dehydration scale assessing more physical findings may help to determine dehydration severity. Most dehydrated children can be treated orally; however, intravenous therapy may be indicated in patients with severe volume depletion, in those who have failed oral therapy, or in children with altered consciousness or significant metabolic abnormalities. Proper management consists of restoring circulatory volume and electrolyte balance. In this paper, we review clinical aspects, diagnosis, and management of children with volume depletion.

Original languageEnglish (US)
Pages (from-to)423-434
Number of pages12
JournalPediatric Nephrology
Issue number2
StatePublished - Feb 2024

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Nephrology

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