Abstract
A fluorometric method for determining bethanidine in blood plasma is described. The bethanidine is extracted into chloroform, a drug‐dye complex with eosin Y is formed, and the fluorescence is measured (excitation, 535 nm; fluorescence, 560 nm). The assay detects 0.02 μM bethanidine (4 ng/ml) in plasma. The relative fluorescence of several body constituents and antihypertensive drugs is negligible. The plasma levels of bethanidine in four hypertensive patients receiving this drug were measured.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 785-788 |
| Number of pages | 4 |
| Journal | Journal of Pharmaceutical Sciences |
| Volume | 64 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 1975 |
All Science Journal Classification (ASJC) codes
- Pharmaceutical Science