fMRI investigation of the cognitive structure of the concealed information test

J. G. Hakun, D. Seelig, K. Ruparel, J. W. Loughead, E. Busch, R. C. Gur, D. D. Langleben

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


We studied the cognitive basis of the functional magnetic resonance imaging (fMRI) pattern of deception in three participants performing the Concealed Information Test (CIT). In all participants, the prefrontoparietal lie activation was similar to the pattern derived from the meta-analysis (N = 40) of our previously reported fMRI CIT studies and was unchanged when the lie response was replaced with passive viewing of the target items. When lies were replaced with irrelevant responses, only the left inferior gyrus activation was common to all subjects. This study presents a systematic strategy for testing the cognitive basis of deception models, and a qualitative approach to single-subject truth-verification fMRI tests.

Original languageEnglish (US)
Pages (from-to)59-67
Number of pages9
Issue number1
StatePublished - Feb 2008

All Science Journal Classification (ASJC) codes

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology


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