TY - JOUR
T1 - Food restriction alters the diurnal distribution of sleep in rats
AU - Roky, Rachida
AU - Kapás, Levente
AU - Taishi, Ping
AU - Fang, Jidong
AU - Krueger, James M.
N1 - Funding Information:
The technical assistance of Mr. Ying Wang is gratefully acknowledged. This research was supported in part by the National Institutes of Health (NS-25378, NS-27250, NS-31453, and NS-30514).
PY - 1999/11
Y1 - 1999/11
N2 - The purpose of the present study was to determine the effects of restricting food and water intake to the light period on sleep and brain temperature (T(br)). Sprague-Dawley male rats were anesthetized and provided with electrodes and thermistors for electroencephalographic (EEG) and T(br) recordings. Baseline recordings were performed after a 3-week recovery period. After baseline recordings, access to food and water was restricted (FWR) to the light period for 29 days. During FWR, the diurnal distribution of rapid-eye-movement sleep (REMS) and T(br) were reversed, while the distribution of non-REMS (NREMS) between the dark and light periods was attenuated. Daily food and water intake, body weight, and the diurnal distribution of EEG slow-wave activity within NREMS remained unchanged. In a separate study, sham-operated and pinealectomized rats were studied in a similar manner. The sleep responses of pinealectomized and sham-operated rats to FWR were similar. Further, FWR did not affect melatonin levels in the sham-operated rats, thereby suggesting that the pineal gland does not mediate the effects of FWR on sleep.
AB - The purpose of the present study was to determine the effects of restricting food and water intake to the light period on sleep and brain temperature (T(br)). Sprague-Dawley male rats were anesthetized and provided with electrodes and thermistors for electroencephalographic (EEG) and T(br) recordings. Baseline recordings were performed after a 3-week recovery period. After baseline recordings, access to food and water was restricted (FWR) to the light period for 29 days. During FWR, the diurnal distribution of rapid-eye-movement sleep (REMS) and T(br) were reversed, while the distribution of non-REMS (NREMS) between the dark and light periods was attenuated. Daily food and water intake, body weight, and the diurnal distribution of EEG slow-wave activity within NREMS remained unchanged. In a separate study, sham-operated and pinealectomized rats were studied in a similar manner. The sleep responses of pinealectomized and sham-operated rats to FWR were similar. Further, FWR did not affect melatonin levels in the sham-operated rats, thereby suggesting that the pineal gland does not mediate the effects of FWR on sleep.
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U2 - 10.1016/S0031-9384(99)00137-7
DO - 10.1016/S0031-9384(99)00137-7
M3 - Article
C2 - 10604840
AN - SCOPUS:0032733307
SN - 0031-9384
VL - 67
SP - 697
EP - 703
JO - Physiology and Behavior
JF - Physiology and Behavior
IS - 5
ER -