TY - JOUR
T1 - FORMATION OF PHOTOPRODUCTS LETHAL FOR HUMAN CELLS IN CULTURE BY DAYLIGHT FLUORESCENT LIGHT AND BILIRUBIN LIGHT
AU - Nixon, B. Tracy
AU - Wang, Richard J.
PY - 1977/12
Y1 - 1977/12
N2 - Abstract. Irradiation of Dulbecco's modified Eagle's tissue culture medium with “Daylight,”“Special Blue,” or “Bilirubin” fluorescent light produces photoproducts lethal to human cells. Killing is abolished when (1) riboflavin, (2) tryptophan and tyrosine, or (3) riboflavin, tryptophan and tyrosine are deleted from medium prior to irradiation with any of the above fluorescent lamps. Toxic photoproducts are also formed when buffered salt solutions containing (a) riboflavin and tryptophan, (b) riboflavin and tyrosine, or (c) riboflavin, tryptophan and tyrosine are exposed to any of these light sources.
AB - Abstract. Irradiation of Dulbecco's modified Eagle's tissue culture medium with “Daylight,”“Special Blue,” or “Bilirubin” fluorescent light produces photoproducts lethal to human cells. Killing is abolished when (1) riboflavin, (2) tryptophan and tyrosine, or (3) riboflavin, tryptophan and tyrosine are deleted from medium prior to irradiation with any of the above fluorescent lamps. Toxic photoproducts are also formed when buffered salt solutions containing (a) riboflavin and tryptophan, (b) riboflavin and tyrosine, or (c) riboflavin, tryptophan and tyrosine are exposed to any of these light sources.
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U2 - 10.1111/j.1751-1097.1977.tb07537.x
DO - 10.1111/j.1751-1097.1977.tb07537.x
M3 - Editorial
C2 - 594185
AN - SCOPUS:0017702119
SN - 0031-8655
VL - 26
SP - 589
EP - 593
JO - Photochemistry and Photobiology
JF - Photochemistry and Photobiology
IS - 6
ER -