FORMATION OF PHOTOPRODUCTS LETHAL FOR HUMAN CELLS IN CULTURE BY DAYLIGHT FLUORESCENT LIGHT AND BILIRUBIN LIGHT

B. Tracy Nixon; Richard J. Wang

doi:10.1111/j.1751-1097.1977.tb07537.x

FORMATION OF PHOTOPRODUCTS LETHAL FOR HUMAN CELLS IN CULTURE BY DAYLIGHT FLUORESCENT LIGHT AND BILIRUBIN LIGHT

B. Tracy Nixon
, Richard J. Wang

Plant Institute

Research output: Contribution to journal › Editorial › peer-review

49 Scopus citations

Abstract

Abstract. Irradiation of Dulbecco's modified Eagle's tissue culture medium with “Daylight,”“Special Blue,” or “Bilirubin” fluorescent light produces photoproducts lethal to human cells. Killing is abolished when (1) riboflavin, (2) tryptophan and tyrosine, or (3) riboflavin, tryptophan and tyrosine are deleted from medium prior to irradiation with any of the above fluorescent lamps. Toxic photoproducts are also formed when buffered salt solutions containing (a) riboflavin and tryptophan, (b) riboflavin and tyrosine, or (c) riboflavin, tryptophan and tyrosine are exposed to any of these light sources.

Original language	English (US)
Pages (from-to)	589-593
Number of pages	5
Journal	Photochemistry and Photobiology
Volume	26
Issue number	6
DOIs	https://doi.org/10.1111/j.1751-1097.1977.tb07537.x
State	Published - Dec 1977

All Science Journal Classification (ASJC) codes

Biochemistry
Physical and Theoretical Chemistry

Access to Document

10.1111/j.1751-1097.1977.tb07537.x

Cite this

@article{1b0c7fd96fea4aafb68359cb6da4193a,

title = "FORMATION OF PHOTOPRODUCTS LETHAL FOR HUMAN CELLS IN CULTURE BY DAYLIGHT FLUORESCENT LIGHT AND BILIRUBIN LIGHT",

abstract = "Abstract. Irradiation of Dulbecco's modified Eagle's tissue culture medium with “Daylight,”“Special Blue,” or “Bilirubin” fluorescent light produces photoproducts lethal to human cells. Killing is abolished when (1) riboflavin, (2) tryptophan and tyrosine, or (3) riboflavin, tryptophan and tyrosine are deleted from medium prior to irradiation with any of the above fluorescent lamps. Toxic photoproducts are also formed when buffered salt solutions containing (a) riboflavin and tryptophan, (b) riboflavin and tyrosine, or (c) riboflavin, tryptophan and tyrosine are exposed to any of these light sources.",

author = "Nixon, \{B. Tracy\} and Wang, \{Richard J.\}",

year = "1977",

month = dec,

doi = "10.1111/j.1751-1097.1977.tb07537.x",

language = "English (US)",

volume = "26",

pages = "589--593",

journal = "Photochemistry and Photobiology",

issn = "0031-8655",

publisher = "John Wiley and Sons Inc.",

number = "6",

}

TY - JOUR

T1 - FORMATION OF PHOTOPRODUCTS LETHAL FOR HUMAN CELLS IN CULTURE BY DAYLIGHT FLUORESCENT LIGHT AND BILIRUBIN LIGHT

AU - Nixon, B. Tracy

AU - Wang, Richard J.

PY - 1977/12

Y1 - 1977/12

N2 - Abstract. Irradiation of Dulbecco's modified Eagle's tissue culture medium with “Daylight,”“Special Blue,” or “Bilirubin” fluorescent light produces photoproducts lethal to human cells. Killing is abolished when (1) riboflavin, (2) tryptophan and tyrosine, or (3) riboflavin, tryptophan and tyrosine are deleted from medium prior to irradiation with any of the above fluorescent lamps. Toxic photoproducts are also formed when buffered salt solutions containing (a) riboflavin and tryptophan, (b) riboflavin and tyrosine, or (c) riboflavin, tryptophan and tyrosine are exposed to any of these light sources.

AB - Abstract. Irradiation of Dulbecco's modified Eagle's tissue culture medium with “Daylight,”“Special Blue,” or “Bilirubin” fluorescent light produces photoproducts lethal to human cells. Killing is abolished when (1) riboflavin, (2) tryptophan and tyrosine, or (3) riboflavin, tryptophan and tyrosine are deleted from medium prior to irradiation with any of the above fluorescent lamps. Toxic photoproducts are also formed when buffered salt solutions containing (a) riboflavin and tryptophan, (b) riboflavin and tyrosine, or (c) riboflavin, tryptophan and tyrosine are exposed to any of these light sources.

UR - https://www.scopus.com/pages/publications/0017702119

UR - https://www.scopus.com/pages/publications/0017702119#tab=citedBy

U2 - 10.1111/j.1751-1097.1977.tb07537.x

DO - 10.1111/j.1751-1097.1977.tb07537.x

M3 - Editorial

C2 - 594185

AN - SCOPUS:0017702119

SN - 0031-8655

VL - 26

SP - 589

EP - 593

JO - Photochemistry and Photobiology

JF - Photochemistry and Photobiology

IS - 6

ER -

FORMATION OF PHOTOPRODUCTS LETHAL FOR HUMAN CELLS IN CULTURE BY DAYLIGHT FLUORESCENT LIGHT AND BILIRUBIN LIGHT

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this