TY - JOUR
T1 - Fragrance contact dermatitis
T2 - A worldwide multicenter investigation (Part II)
AU - Larsen, Walter
AU - Nakayama, Hideo
AU - Fischer, Torkil
AU - Elsner, Peter
AU - Frosch, Peter
AU - Burrows, Desmond
AU - Jordan, William
AU - Shaw, Stephanie
AU - Wilkinson, John
AU - Marks, James
AU - Sugawara, M.
AU - Nethercott, Marc
AU - Nethercott, James
PY - 2001
Y1 - 2001
N2 - The purpose of this study was to determine the frequency of responses to selected fragrance materials in patients who were fragrance sensitive. 178 patients were evaluated in 8 centers worldwide with a fragrance mix (FM) and 20 other fragrance materials. Reaction to the fragrance mixture (FM) occurred in 78.7% of the subjects. Substances reacting at a rate of 2% or higher included jasmine absolute, geranium oil bourbon, 1-citronellol, spearmint oil, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-γ-2-benzopyran, omega-6-hexadecenlactone, dimethyltetrahydrobenzaldehyde (isomer mixture), and α-amylcinnamaldehyde. These chemicals should be furthur evaluated to corroborate their allergenicity. We are constantly looking for new fragrance allergens to extend the diagnostic capability of the fragrance mix (FM).
AB - The purpose of this study was to determine the frequency of responses to selected fragrance materials in patients who were fragrance sensitive. 178 patients were evaluated in 8 centers worldwide with a fragrance mix (FM) and 20 other fragrance materials. Reaction to the fragrance mixture (FM) occurred in 78.7% of the subjects. Substances reacting at a rate of 2% or higher included jasmine absolute, geranium oil bourbon, 1-citronellol, spearmint oil, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-γ-2-benzopyran, omega-6-hexadecenlactone, dimethyltetrahydrobenzaldehyde (isomer mixture), and α-amylcinnamaldehyde. These chemicals should be furthur evaluated to corroborate their allergenicity. We are constantly looking for new fragrance allergens to extend the diagnostic capability of the fragrance mix (FM).
UR - http://www.scopus.com/inward/record.url?scp=0034985504&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034985504&partnerID=8YFLogxK
U2 - 10.1034/j.1600-0536.2001.044006344.x
DO - 10.1034/j.1600-0536.2001.044006344.x
M3 - Article
C2 - 11380544
AN - SCOPUS:0034985504
SN - 0105-1873
VL - 44
SP - 344
EP - 346
JO - Contact Dermatitis
JF - Contact Dermatitis
IS - 6
ER -