TY - JOUR
T1 - Frequency Domain Simultaneous Source and Source Coherence Estimation with an Application to MEG
AU - Grasman, Raoul P.P.P.
AU - Huizenga, Hilde M.
AU - Waldorp, Lourens J.
AU - Böcker, Koen B.E.
AU - Molenaar, Peter C.M.
N1 - Funding Information:
Manuscript received June 19, 2002; revised April 18, 2003. This work was supported by The Netherlands Organization for Scientific Research (NWO) through the NWO foundation for Behavioral and Educational Sciences under a grant awarded to H. M. Huizenga, and P. C. M. Molenaar. The work of H. M. Huizenga was also supported in part by a KNAW fellowship. The work of R. P. P. P. Grasman was supported in part by the NWO under Grant 527-25-014. The work of L. J. Waldorp was supported by the NWO under Grant 527-25-013. The work of K. B. E. Böcker was supported by the NWO under Grant 527-25-015. *R. P. P. P. Grasman is with the Department of Psychology, University of Amsterdam, Roetersstraat 15, 1018WB Amsterdam, The Netherlands (e-mail: [email protected]).
PY - 2004/1
Y1 - 2004/1
N2 - Interactions between cortical areas are crucial for cognitive functioning. Methods currently in use to assess such interactions are not well suited for this task because they lack timing precision, localization precision, or both. We present a method for simultaneous estimation of source location and orientation parameters and cross-spectral parameters to overcome these problems. Different estimators are evaluated for their performance. From a simulation study, we conclude that the estimators derived from the maximum-likelihood procedure have good statistical properties with moderate sample sizes, whereas those obtained from the generalized least squares procedure are biased and give poor-quality standard errors. The method is illustrated with visually evoked field data, with inconclusive results.
AB - Interactions between cortical areas are crucial for cognitive functioning. Methods currently in use to assess such interactions are not well suited for this task because they lack timing precision, localization precision, or both. We present a method for simultaneous estimation of source location and orientation parameters and cross-spectral parameters to overcome these problems. Different estimators are evaluated for their performance. From a simulation study, we conclude that the estimators derived from the maximum-likelihood procedure have good statistical properties with moderate sample sizes, whereas those obtained from the generalized least squares procedure are biased and give poor-quality standard errors. The method is illustrated with visually evoked field data, with inconclusive results.
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U2 - 10.1109/TBME.2003.820385
DO - 10.1109/TBME.2003.820385
M3 - Article
C2 - 14723493
AN - SCOPUS:0347517844
SN - 0018-9294
VL - 51
SP - 45
EP - 55
JO - IEEE Transactions on Biomedical Engineering
JF - IEEE Transactions on Biomedical Engineering
IS - 1
ER -