Abstract
We reported that hydrogel nanoparticles (nanogels) were formed by self-assembly of cholesterol group bearing pullulans (CHP). We synthesized various cationic groups bearing CHP. The cationic CHP formed monodisperse cationic nanogels (30-40 nm) in water. In this study, we investigated the characteristic of cationic nanogels-nucleic acid complexes. Furthermore, I investigated the interaction between cationic nanogels-nucleic acid complexes and cells. The results indicate that various cationic nanogels and nucleic acid were complexed and formed nanosize particles. The CHP nanogel which modified spermine acts as efficient nucleic acid carrier in cells.
| Original language | English (US) |
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| Pages | 5463-5464 |
| Number of pages | 2 |
| State | Published - 2006 |
| Event | 55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan Duration: Sep 20 2006 → Sep 22 2006 |
Conference
| Conference | 55th Society of Polymer Science Japan Symposium on Macromolecules |
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| Country/Territory | Japan |
| City | Toyama |
| Period | 9/20/06 → 9/22/06 |
All Science Journal Classification (ASJC) codes
- General Engineering