Functional near-infrared neuroimaging

Meltem Izzetoglu, Kurtulus Izzetoglu, Scott Bunce, Hasan Ayaz, Ajit Devaraj, Banu Onaral, Kambiz Pourrezaei

Research output: Contribution to journalArticlepeer-review

203 Scopus citations


Functional near-infrared spectroscopy (fNIR) is a neroimaging modality that enables continuous, noninvasive, and portable monitoring of changes in blood oxygenation and blood volume related to human brain function. Over the last decade, studies in the laboratory have established that fNIR spectroscopy provides a veridical measure of oxygenation and blood flow in the brain. Our recent findings indicate that fNIR can effectively monitor cognitive tasks such as attention, working memory, target categorization, and problem solving. These experimental outcomes compare favorably with functional magnetic resonance imaging (fMRI) studies, and in particular, with the blood oxygenation level dependent signal. Since fNIR can be implemented in the form of a wearable and minimally intrusive device, it has the capacity to monitor brain activity under real life conditions and in everyday environments. Moreover, the fNIR system is amenable to integration with other established physiological and neurobehavioral measures, including electroencephalogram, eye tracking, pupil reflex, heart rate variability, respiration, and electrodermal activity.

Original languageEnglish (US)
Pages (from-to)153-159
Number of pages7
JournalIEEE Transactions on Neural Systems and Rehabilitation Engineering
Issue number2
StatePublished - Jun 2005

All Science Journal Classification (ASJC) codes

  • Rehabilitation
  • General Neuroscience
  • Internal Medicine
  • Biomedical Engineering


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