Abstract
Abstract The carbofunctionalization of 2-bromo-N-benzyl indole via lithium-bromide exchange is presented. The reaction scope is demonstrated by providing a variety of substrate examples that deliver carbofunctionalized products in good-to-excellent yields. The competition between nucleophilic addition and proton transfer is discussed.
Original language | English (US) |
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Article number | 45701 |
Pages (from-to) | 3564-3566 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 56 |
Issue number | 23 |
DOIs | |
State | Published - May 25 2015 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry