Functionalization of 2-bromo-N-benzyl indole via lithium-bromide exchange

Ken S. Feldman; Inanllely Y. Gonzalez; Jocelyn E. Brown

doi:10.1016/j.tetlet.2015.01.032

Functionalization of 2-bromo-N-benzyl indole via lithium-bromide exchange

Ken S. Feldman
, Inanllely Y. Gonzalez
, Jocelyn E. Brown

Chemistry

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Abstract The carbofunctionalization of 2-bromo-N-benzyl indole via lithium-bromide exchange is presented. The reaction scope is demonstrated by providing a variety of substrate examples that deliver carbofunctionalized products in good-to-excellent yields. The competition between nucleophilic addition and proton transfer is discussed.

Original language	English (US)
Article number	45701
Pages (from-to)	3564-3566
Number of pages	3
Journal	Tetrahedron Letters
Volume	56
Issue number	23
DOIs	https://doi.org/10.1016/j.tetlet.2015.01.032
State	Published - May 25 2015

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2015.01.032

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title = "Functionalization of 2-bromo-N-benzyl indole via lithium-bromide exchange",

abstract = "Abstract The carbofunctionalization of 2-bromo-N-benzyl indole via lithium-bromide exchange is presented. The reaction scope is demonstrated by providing a variety of substrate examples that deliver carbofunctionalized products in good-to-excellent yields. The competition between nucleophilic addition and proton transfer is discussed.",

author = "Feldman, \{Ken S.\} and Gonzalez, \{Inanllely Y.\} and Brown, \{Jocelyn E.\}",

year = "2015",

month = may,

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doi = "10.1016/j.tetlet.2015.01.032",

language = "English (US)",

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pages = "3564--3566",

journal = "Tetrahedron Letters",

issn = "0040-4039",

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number = "23",

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TY - JOUR

T1 - Functionalization of 2-bromo-N-benzyl indole via lithium-bromide exchange

AU - Feldman, Ken S.

AU - Gonzalez, Inanllely Y.

AU - Brown, Jocelyn E.

PY - 2015/5/25

Y1 - 2015/5/25

N2 - Abstract The carbofunctionalization of 2-bromo-N-benzyl indole via lithium-bromide exchange is presented. The reaction scope is demonstrated by providing a variety of substrate examples that deliver carbofunctionalized products in good-to-excellent yields. The competition between nucleophilic addition and proton transfer is discussed.

AB - Abstract The carbofunctionalization of 2-bromo-N-benzyl indole via lithium-bromide exchange is presented. The reaction scope is demonstrated by providing a variety of substrate examples that deliver carbofunctionalized products in good-to-excellent yields. The competition between nucleophilic addition and proton transfer is discussed.

UR - https://www.scopus.com/pages/publications/84929587203

UR - https://www.scopus.com/pages/publications/84929587203#tab=citedBy

U2 - 10.1016/j.tetlet.2015.01.032

DO - 10.1016/j.tetlet.2015.01.032

M3 - Article

AN - SCOPUS:84929587203

SN - 0040-4039

VL - 56

SP - 3564

EP - 3566

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 23

M1 - 45701

ER -

Functionalization of 2-bromo-N-benzyl indole via lithium-bromide exchange

Abstract

All Science Journal Classification (ASJC) codes

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