TY - JOUR
T1 - FUNCTIONALLY-ACTIVE POLYPHOSPHAZENES AS REACTION PRECURSORS TO BIOLOGICALLY-ACTIVE MACROMOLECULES.
AU - Allcock, Harry R.
AU - Austin, Paul E.
AU - Neenan, Thomas X.
PY - 1985/4
Y1 - 1985/4
N2 - The classical route for the synthesis of poly(organophosphazenes) involves the use of poly(dichlorophosphazene) as a reactive intermediate for halogen substitution reactions by organic nucleophiles. Such reactions have been employed for the binding of a wide range of biologically active organic units, including catecholamines, polypeptides, procaine, sulfadiazine, etc. In at least one case (dopamine) biological activity has been demonstrated even by the solid, reagent-bound polymer.
AB - The classical route for the synthesis of poly(organophosphazenes) involves the use of poly(dichlorophosphazene) as a reactive intermediate for halogen substitution reactions by organic nucleophiles. Such reactions have been employed for the binding of a wide range of biologically active organic units, including catecholamines, polypeptides, procaine, sulfadiazine, etc. In at least one case (dopamine) biological activity has been demonstrated even by the solid, reagent-bound polymer.
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M3 - Conference article
AN - SCOPUS:0347991475
SN - 0032-3934
VL - 26
JO - American Chemical Society, Polymer Preprints, Division of Polymer Chemistry
JF - American Chemical Society, Polymer Preprints, Division of Polymer Chemistry
IS - 1
ER -