FUNCTIONALLY-ACTIVE POLYPHOSPHAZENES AS REACTION PRECURSORS TO BIOLOGICALLY-ACTIVE MACROMOLECULES.

Harry R. Allcock; Paul E. Austin; Thomas X. Neenan

FUNCTIONALLY-ACTIVE POLYPHOSPHAZENES AS REACTION PRECURSORS TO BIOLOGICALLY-ACTIVE MACROMOLECULES.

Harry R. Allcock
, Paul E. Austin
, Thomas X. Neenan

Research output: Contribution to journal › Conference article › peer-review

Abstract

The classical route for the synthesis of poly(organophosphazenes) involves the use of poly(dichlorophosphazene) as a reactive intermediate for halogen substitution reactions by organic nucleophiles. Such reactions have been employed for the binding of a wide range of biologically active organic units, including catecholamines, polypeptides, procaine, sulfadiazine, etc. In at least one case (dopamine) biological activity has been demonstrated even by the solid, reagent-bound polymer.

Original language	English (US)
Number of pages	1
Journal	American Chemical Society, Polymer Preprints, Division of Polymer Chemistry
Volume	26
Issue number	1
State	Published - Apr 1985

All Science Journal Classification (ASJC) codes

Polymers and Plastics

Cite this

@article{309f51eca2d044489fae2ac144276cca,

title = "FUNCTIONALLY-ACTIVE POLYPHOSPHAZENES AS REACTION PRECURSORS TO BIOLOGICALLY-ACTIVE MACROMOLECULES.",

abstract = "The classical route for the synthesis of poly(organophosphazenes) involves the use of poly(dichlorophosphazene) as a reactive intermediate for halogen substitution reactions by organic nucleophiles. Such reactions have been employed for the binding of a wide range of biologically active organic units, including catecholamines, polypeptides, procaine, sulfadiazine, etc. In at least one case (dopamine) biological activity has been demonstrated even by the solid, reagent-bound polymer.",

author = "Allcock, \{Harry R.\} and Austin, \{Paul E.\} and Neenan, \{Thomas X.\}",

year = "1985",

month = apr,

language = "English (US)",

volume = "26",

journal = "American Chemical Society, Polymer Preprints, Division of Polymer Chemistry",

issn = "0032-3934",

number = "1",

}

TY - JOUR

T1 - FUNCTIONALLY-ACTIVE POLYPHOSPHAZENES AS REACTION PRECURSORS TO BIOLOGICALLY-ACTIVE MACROMOLECULES.

AU - Allcock, Harry R.

AU - Austin, Paul E.

AU - Neenan, Thomas X.

PY - 1985/4

Y1 - 1985/4

N2 - The classical route for the synthesis of poly(organophosphazenes) involves the use of poly(dichlorophosphazene) as a reactive intermediate for halogen substitution reactions by organic nucleophiles. Such reactions have been employed for the binding of a wide range of biologically active organic units, including catecholamines, polypeptides, procaine, sulfadiazine, etc. In at least one case (dopamine) biological activity has been demonstrated even by the solid, reagent-bound polymer.

AB - The classical route for the synthesis of poly(organophosphazenes) involves the use of poly(dichlorophosphazene) as a reactive intermediate for halogen substitution reactions by organic nucleophiles. Such reactions have been employed for the binding of a wide range of biologically active organic units, including catecholamines, polypeptides, procaine, sulfadiazine, etc. In at least one case (dopamine) biological activity has been demonstrated even by the solid, reagent-bound polymer.

UR - https://www.scopus.com/pages/publications/0347991475

UR - https://www.scopus.com/pages/publications/0347991475#tab=citedBy

M3 - Conference article

AN - SCOPUS:0347991475

SN - 0032-3934

VL - 26

JO - American Chemical Society, Polymer Preprints, Division of Polymer Chemistry

JF - American Chemical Society, Polymer Preprints, Division of Polymer Chemistry

IS - 1

ER -

FUNCTIONALLY-ACTIVE POLYPHOSPHAZENES AS REACTION PRECURSORS TO BIOLOGICALLY-ACTIVE MACROMOLECULES.

Abstract

All Science Journal Classification (ASJC) codes

Other files and links

Fingerprint

Cite this