Fungal cytochrome P450 database

Jongsun Park; Seungmin Lee; Jaeyoung Choi; Kyohun Ahn; Bongsoo Park; Jaejin Park; Seogchana Kang; Yong Hwan Lee

doi:10.1186/1471-2164-9-402

Fungal cytochrome P450 database

Jongsun Park, Seungmin Lee, Jaeyoung Choi, Kyohun Ahn, Bongsoo Park, Jaejin Park, Seogchana Kang, Yong Hwan Lee

Research output: Contribution to journal › Article › peer-review

137 Scopus citations

Abstract

Background: Cytochrome P450 enzymes play critical roles in fungal biology and ecology. To support studies on the roles and evolution of cytochrome P450 enzymes in fungi based on rapidly accumulating genome sequences from diverse fungal species, an efficient bioinformatics platform specialized for this super family of proteins is highly desirable. Results: The Fungal Cytochrome P450 Database (FCPD) archives genes encoding P450s in the genomes of 66 fungal and 4 oomycete species (4,538 in total) and supports analyses of their sequences, chromosomal distribution pattern, and evolutionary histories and relationships. The archived P450s were classified into 16 classes based on InterPro terms and clustered into 141 groups using tribe-MCL. The proportion of P450s in the total proteome and class distribution in individual species exhibited certain taxon-specific characteristics. Conclusion: The FCPD will facilitate systematic identification and multifaceted analyses of P450s at multiple taxon levels via the web. All data and functions are available at the web site http://p450.riceblast.snu.ac.kr/.

Original language	English (US)
Article number	402
Journal	BMC genomics
Volume	9
DOIs	https://doi.org/10.1186/1471-2164-9-402
State	Published - Aug 28 2008

All Science Journal Classification (ASJC) codes

Biotechnology
Genetics

Access to Document

10.1186/1471-2164-9-402

Cite this

@article{123ddf5f81884ec6be2eff22919495b3,

title = "Fungal cytochrome P450 database",

abstract = "Background: Cytochrome P450 enzymes play critical roles in fungal biology and ecology. To support studies on the roles and evolution of cytochrome P450 enzymes in fungi based on rapidly accumulating genome sequences from diverse fungal species, an efficient bioinformatics platform specialized for this super family of proteins is highly desirable. Results: The Fungal Cytochrome P450 Database (FCPD) archives genes encoding P450s in the genomes of 66 fungal and 4 oomycete species (4,538 in total) and supports analyses of their sequences, chromosomal distribution pattern, and evolutionary histories and relationships. The archived P450s were classified into 16 classes based on InterPro terms and clustered into 141 groups using tribe-MCL. The proportion of P450s in the total proteome and class distribution in individual species exhibited certain taxon-specific characteristics. Conclusion: The FCPD will facilitate systematic identification and multifaceted analyses of P450s at multiple taxon levels via the web. All data and functions are available at the web site http://p450.riceblast.snu.ac.kr/.",

author = "Jongsun Park and Seungmin Lee and Jaeyoung Choi and Kyohun Ahn and Bongsoo Park and Jaejin Park and Seogchana Kang and Lee, {Yong Hwan}",

note = "Funding Information: This research was partially supported by grants from Crop Functional Genomics Center (CG1141) and a grant from Biogreen21 Project (20080401034044) funded by the Rural Development Administration to Y.H.L. A USDA-NRI grant to S.K. (2008-55605-18773) also supported this work. J.P. thanks to graduate fellowship provided by the Ministry of Education through the Brain Korea 21 Project.",

year = "2008",

month = aug,

day = "28",

doi = "10.1186/1471-2164-9-402",

language = "English (US)",

volume = "9",

journal = "BMC genomics",

issn = "1471-2164",

publisher = "BioMed Central",

}

TY - JOUR

T1 - Fungal cytochrome P450 database

AU - Park, Jongsun

AU - Lee, Seungmin

AU - Choi, Jaeyoung

AU - Ahn, Kyohun

AU - Park, Bongsoo

AU - Park, Jaejin

AU - Kang, Seogchana

AU - Lee, Yong Hwan

N1 - Funding Information: This research was partially supported by grants from Crop Functional Genomics Center (CG1141) and a grant from Biogreen21 Project (20080401034044) funded by the Rural Development Administration to Y.H.L. A USDA-NRI grant to S.K. (2008-55605-18773) also supported this work. J.P. thanks to graduate fellowship provided by the Ministry of Education through the Brain Korea 21 Project.

PY - 2008/8/28

Y1 - 2008/8/28

N2 - Background: Cytochrome P450 enzymes play critical roles in fungal biology and ecology. To support studies on the roles and evolution of cytochrome P450 enzymes in fungi based on rapidly accumulating genome sequences from diverse fungal species, an efficient bioinformatics platform specialized for this super family of proteins is highly desirable. Results: The Fungal Cytochrome P450 Database (FCPD) archives genes encoding P450s in the genomes of 66 fungal and 4 oomycete species (4,538 in total) and supports analyses of their sequences, chromosomal distribution pattern, and evolutionary histories and relationships. The archived P450s were classified into 16 classes based on InterPro terms and clustered into 141 groups using tribe-MCL. The proportion of P450s in the total proteome and class distribution in individual species exhibited certain taxon-specific characteristics. Conclusion: The FCPD will facilitate systematic identification and multifaceted analyses of P450s at multiple taxon levels via the web. All data and functions are available at the web site http://p450.riceblast.snu.ac.kr/.

AB - Background: Cytochrome P450 enzymes play critical roles in fungal biology and ecology. To support studies on the roles and evolution of cytochrome P450 enzymes in fungi based on rapidly accumulating genome sequences from diverse fungal species, an efficient bioinformatics platform specialized for this super family of proteins is highly desirable. Results: The Fungal Cytochrome P450 Database (FCPD) archives genes encoding P450s in the genomes of 66 fungal and 4 oomycete species (4,538 in total) and supports analyses of their sequences, chromosomal distribution pattern, and evolutionary histories and relationships. The archived P450s were classified into 16 classes based on InterPro terms and clustered into 141 groups using tribe-MCL. The proportion of P450s in the total proteome and class distribution in individual species exhibited certain taxon-specific characteristics. Conclusion: The FCPD will facilitate systematic identification and multifaceted analyses of P450s at multiple taxon levels via the web. All data and functions are available at the web site http://p450.riceblast.snu.ac.kr/.

UR - http://www.scopus.com/inward/record.url?scp=52449096190&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=52449096190&partnerID=8YFLogxK

U2 - 10.1186/1471-2164-9-402

DO - 10.1186/1471-2164-9-402

M3 - Article

C2 - 18755027

AN - SCOPUS:52449096190

SN - 1471-2164

VL - 9

JO - BMC genomics

JF - BMC genomics

M1 - 402

ER -

Fungal cytochrome P450 database

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this