FunMap: Functional mapping of complex traits

Chang Xing Ma; Rongling Wu; George Casella

doi:10.1093/bioinformatics/bth156

FunMap: Functional mapping of complex traits

Chang Xing Ma, Rongling Wu, George Casella

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Summary: FunMap is a Web-based user interface designed to map quantitative trait loci (QTL) affecting function-valued traits or infinite-dimensional traits in well-structured pedigrees or natural populations. User input includes three files: longitudinal trait data, marker genotypes and/or a linkage map. This software allows for a systematic genome-wide scan and significance test of QTL throughout the map. The dynamic change of QTL effects during the time course of growth is automatically drawn, from which specific biological hypotheses regarding the genetic control mechanisms of growth and development can be tested.

Original language	English (US)
Pages (from-to)	1808-1811
Number of pages	4
Journal	Bioinformatics
Volume	20
Issue number	11
DOIs	https://doi.org/10.1093/bioinformatics/bth156
State	Published - Jul 22 2004

All Science Journal Classification (ASJC) codes

Statistics and Probability
Biochemistry
Molecular Biology
Computer Science Applications
Computational Theory and Mathematics
Computational Mathematics

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10.1093/bioinformatics/bth156

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abstract = "Summary: FunMap is a Web-based user interface designed to map quantitative trait loci (QTL) affecting function-valued traits or infinite-dimensional traits in well-structured pedigrees or natural populations. User input includes three files: longitudinal trait data, marker genotypes and/or a linkage map. This software allows for a systematic genome-wide scan and significance test of QTL throughout the map. The dynamic change of QTL effects during the time course of growth is automatically drawn, from which specific biological hypotheses regarding the genetic control mechanisms of growth and development can be tested.",

author = "Ma, {Chang Xing} and Rongling Wu and George Casella",

note = "Funding Information: This work is partially supported by an Outstanding Young Investigators Award of the National Science Foundation of China (30128017), a University of Florida Research Opportunity Fund (02050259) and a University of South Florida Biodefense grant (7222061-12) to R.W. The publication of this manuscript is approved as journal series no. R-10066 by the Florida Agricultural Experiment Station.",

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doi = "10.1093/bioinformatics/bth156",

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T2 - Functional mapping of complex traits

AU - Ma, Chang Xing

AU - Wu, Rongling

AU - Casella, George

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Y1 - 2004/7/22

N2 - Summary: FunMap is a Web-based user interface designed to map quantitative trait loci (QTL) affecting function-valued traits or infinite-dimensional traits in well-structured pedigrees or natural populations. User input includes three files: longitudinal trait data, marker genotypes and/or a linkage map. This software allows for a systematic genome-wide scan and significance test of QTL throughout the map. The dynamic change of QTL effects during the time course of growth is automatically drawn, from which specific biological hypotheses regarding the genetic control mechanisms of growth and development can be tested.

AB - Summary: FunMap is a Web-based user interface designed to map quantitative trait loci (QTL) affecting function-valued traits or infinite-dimensional traits in well-structured pedigrees or natural populations. User input includes three files: longitudinal trait data, marker genotypes and/or a linkage map. This software allows for a systematic genome-wide scan and significance test of QTL throughout the map. The dynamic change of QTL effects during the time course of growth is automatically drawn, from which specific biological hypotheses regarding the genetic control mechanisms of growth and development can be tested.

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FunMap: Functional mapping of complex traits

Abstract

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