GABA as an inhibitory transmitter in the pigeon isthmo-tectal pathway

Dominik Felix; Gang Yi Wu; Shu Rong Wang

doi:10.1016/0304-3940(94)90394-8

GABA as an inhibitory transmitter in the pigeon isthmo-tectal pathway

Dominik Felix, Gang Yi Wu, Shu Rong Wang

Biology

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

In the present investigation, the effects of inhibitory amino acids and their antagonists were tested on isthmo-tectal projection in the pigeon. The majority of superficial tectal cells are inhibited following stimulation of the parvocellular division of nucleus isthmi. A smaller portion of tectal cells showed excitatory responses followed by an inhibitory period. Both inhibitory mechanisms are blocked by the specific γ-aminobutyric acid (GABA)-antagonist bicuculline but not by strychnine. Our results support the idea that GABA acts as an inhibitory neurotransmitter in the pigeon isthmo-tectal pathways.

Original language	English (US)
Pages (from-to)	212-214
Number of pages	3
Journal	Neuroscience letters
Volume	169
Issue number	1-2
DOIs	https://doi.org/10.1016/0304-3940(94)90394-8
State	Published - Mar 14 1994

All Science Journal Classification (ASJC) codes

General Neuroscience

Access to Document

10.1016/0304-3940(94)90394-8

Cite this

@article{c841441f98fa4079b5a3d7fbf78325d9,

title = "GABA as an inhibitory transmitter in the pigeon isthmo-tectal pathway",

abstract = "In the present investigation, the effects of inhibitory amino acids and their antagonists were tested on isthmo-tectal projection in the pigeon. The majority of superficial tectal cells are inhibited following stimulation of the parvocellular division of nucleus isthmi. A smaller portion of tectal cells showed excitatory responses followed by an inhibitory period. Both inhibitory mechanisms are blocked by the specific γ-aminobutyric acid (GABA)-antagonist bicuculline but not by strychnine. Our results support the idea that GABA acts as an inhibitory neurotransmitter in the pigeon isthmo-tectal pathways.",

author = "Dominik Felix and Wu, \{Gang Yi\} and Wang, \{Shu Rong\}",

year = "1994",

month = mar,

day = "14",

doi = "10.1016/0304-3940(94)90394-8",

language = "English (US)",

volume = "169",

pages = "212--214",

journal = "Neuroscience letters",

issn = "0304-3940",

publisher = "Elsevier Ireland Ltd",

number = "1-2",

}

TY - JOUR

T1 - GABA as an inhibitory transmitter in the pigeon isthmo-tectal pathway

AU - Felix, Dominik

AU - Wu, Gang Yi

AU - Wang, Shu Rong

PY - 1994/3/14

Y1 - 1994/3/14

N2 - In the present investigation, the effects of inhibitory amino acids and their antagonists were tested on isthmo-tectal projection in the pigeon. The majority of superficial tectal cells are inhibited following stimulation of the parvocellular division of nucleus isthmi. A smaller portion of tectal cells showed excitatory responses followed by an inhibitory period. Both inhibitory mechanisms are blocked by the specific γ-aminobutyric acid (GABA)-antagonist bicuculline but not by strychnine. Our results support the idea that GABA acts as an inhibitory neurotransmitter in the pigeon isthmo-tectal pathways.

AB - In the present investigation, the effects of inhibitory amino acids and their antagonists were tested on isthmo-tectal projection in the pigeon. The majority of superficial tectal cells are inhibited following stimulation of the parvocellular division of nucleus isthmi. A smaller portion of tectal cells showed excitatory responses followed by an inhibitory period. Both inhibitory mechanisms are blocked by the specific γ-aminobutyric acid (GABA)-antagonist bicuculline but not by strychnine. Our results support the idea that GABA acts as an inhibitory neurotransmitter in the pigeon isthmo-tectal pathways.

UR - https://www.scopus.com/pages/publications/0028213731

UR - https://www.scopus.com/inward/citedby.url?scp=0028213731&partnerID=8YFLogxK

U2 - 10.1016/0304-3940(94)90394-8

DO - 10.1016/0304-3940(94)90394-8

M3 - Article

C2 - 7914015

AN - SCOPUS:0028213731

SN - 0304-3940

VL - 169

SP - 212

EP - 214

JO - Neuroscience letters

JF - Neuroscience letters

IS - 1-2

ER -

GABA as an inhibitory transmitter in the pigeon isthmo-tectal pathway

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this