Galaxy: A platform for interactive large-scale genome analysis

  • Belinda Giardine
  • , Cathy Riemer
  • , Ross C. Hardison
  • , Richard Burhans
  • , Laura Elnitski
  • , Prachi Shah
  • , Yi Zhang
  • , Daniel Blankenberg
  • , Istvan Albert
  • , James Taylor
  • , Webb Miller
  • , W. James Kent
  • , Anton Nekrutenko

Research output: Contribution to journalArticlepeer-review

Abstract

Accessing and analyzing the exponentially expanding genomic sequence and functional data pose a challenge for biomedical researchers. Here we describe an interactive system, Galaxy, that combines the power of existing genome annotation databases with a simple Web portal to enable users to search remote resources, combine data from independent queries, and visualize the results. The heart of Galaxy is a flexible history system that stores the queries from each user; performs operations such as intersections, unions, and subtractions; and links to other computational tools. Galaxy can be accessed at http://g2.bx.psu.edu.

Original languageEnglish (US)
Pages (from-to)1451-1455
Number of pages5
JournalGenome research
Volume15
Issue number10
DOIs
StatePublished - Oct 2005

All Science Journal Classification (ASJC) codes

  • Genetics
  • Genetics(clinical)

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