Generation of aza-ortho-xylylenes via ring opening of 2-(2-acylaminophenyl) aziridines: Application in the construction of the communesin ring system

Seth L. Crawley; Raymond L. Funk

doi:10.1021/ol061461d

Generation of aza-ortho-xylylenes via ring opening of 2-(2-acylaminophenyl) aziridines: Application in the construction of the communesin ring system

Seth L. Crawley, Raymond L. Funk

Chemistry

Research output: Contribution to journal › Article › peer-review

91 Scopus citations

Abstract

A new protocol for generating aza-ortho-xylylenes via acid-catalyzed or fluoride-promoted ring opening of 2-(2-acylaminophenyl)aziridines is described. This methodology has been exploited in the rapid construction of a hexacyclic substructure of communesin B.

Original language	English (US)
Pages (from-to)	3995-3998
Number of pages	4
Journal	Organic Letters
Volume	8
Issue number	18
DOIs	https://doi.org/10.1021/ol061461d
State	Published - Aug 31 2006

All Science Journal Classification (ASJC) codes

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol061461d

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abstract = "A new protocol for generating aza-ortho-xylylenes via acid-catalyzed or fluoride-promoted ring opening of 2-(2-acylaminophenyl)aziridines is described. This methodology has been exploited in the rapid construction of a hexacyclic substructure of communesin B.",

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AU - Funk, Raymond L.

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Y1 - 2006/8/31

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AB - A new protocol for generating aza-ortho-xylylenes via acid-catalyzed or fluoride-promoted ring opening of 2-(2-acylaminophenyl)aziridines is described. This methodology has been exploited in the rapid construction of a hexacyclic substructure of communesin B.

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Generation of aza-ortho-xylylenes via ring opening of 2-(2-acylaminophenyl) aziridines: Application in the construction of the communesin ring system

Abstract

All Science Journal Classification (ASJC) codes

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