Generation of ketenes from carboxylic acids using the mukaiyama reagent (1-methyl-2-chloropyridinium iodide)

Raymond L. Funk, Matthew M. Abelman, Kay M. Jellison

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

Ketenes can be generated by treatment of carboxylic acids with l-methyl-2-chloropyridinium iodide and triethylamine and may be intermediates during macrolactonization reactions via the Mukaiyama procedure. A new procedure for the direct conversion of enoic acids to [2+2] ketene-olefin cydoadducts is described.

Original languageEnglish (US)
Pages (from-to)36-37
Number of pages2
JournalSynlett
Volume1989
Issue number1
DOIs
StatePublished - Sep 1989

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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