Genetic analysis of Israel acute paralysis virus: Distinct clusters are circulating in the United States

G. Palacios; J. Hui; P. L. Quan; A. Kalkstein; K. S. Honkavuori; A. V. Bussetti; S. Conlan; J. Evans; Y. P. Chen; D. VanEngelsdorp; H. Efrat; J. Pettis; D. Cox-Foster; E. C. Holmes; T. Briese; W. I. Lipkin

doi:10.1128/JVI.00251-08

Genetic analysis of Israel acute paralysis virus: Distinct clusters are circulating in the United States

G. Palacios, J. Hui, P. L. Quan, A. Kalkstein, K. S. Honkavuori, A. V. Bussetti, S. Conlan, J. Evans, Y. P. Chen, D. VanEngelsdorp, H. Efrat, J. Pettis, D. Cox-Foster, E. C. Holmes, T. Briese, W. I. Lipkin

Entomology

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96 Scopus citations

Abstract

Israel acute paralysis virus (IAPV) is associated with colony collapse disorder of honey bees. Nonetheless, its role in the pathogenesis of the disorder and its geographic distribution are unclear. Here, we report phylogenetic analysis of IAPV obtained from bees in the United States, Canada, Australia, and Israel and the establishment of diagnostic real-time PCR assays for IAPV detection. Our data indicate the existence of at least three distinct IAPV lineages, two of them circulating in the United States. Analysis of representatives from each proposed lineage suggested the possibility of recombination events and revealed differences in coding sequences that may have implications for virulence.

Original language	English (US)
Pages (from-to)	6209-6217
Number of pages	9
Journal	Journal of virology
Volume	82
Issue number	13
DOIs	https://doi.org/10.1128/JVI.00251-08
State	Published - Jul 2008

All Science Journal Classification (ASJC) codes

Microbiology
Immunology
Insect Science
Virology

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Palacios, G., Hui, J., Quan, P. L., Kalkstein, A., Honkavuori, K. S., Bussetti, A. V., Conlan, S., Evans, J., Chen, Y. P., VanEngelsdorp, D., Efrat, H., Pettis, J., Cox-Foster, D., Holmes, E. C., Briese, T., & Lipkin, W. I. (2008). Genetic analysis of Israel acute paralysis virus: Distinct clusters are circulating in the United States. Journal of virology, 82(13), 6209-6217. https://doi.org/10.1128/JVI.00251-08

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title = "Genetic analysis of Israel acute paralysis virus: Distinct clusters are circulating in the United States",

abstract = "Israel acute paralysis virus (IAPV) is associated with colony collapse disorder of honey bees. Nonetheless, its role in the pathogenesis of the disorder and its geographic distribution are unclear. Here, we report phylogenetic analysis of IAPV obtained from bees in the United States, Canada, Australia, and Israel and the establishment of diagnostic real-time PCR assays for IAPV detection. Our data indicate the existence of at least three distinct IAPV lineages, two of them circulating in the United States. Analysis of representatives from each proposed lineage suggested the possibility of recombination events and revealed differences in coding sequences that may have implications for virulence.",

author = "G. Palacios and J. Hui and Quan, {P. L.} and A. Kalkstein and Honkavuori, {K. S.} and Bussetti, {A. V.} and S. Conlan and J. Evans and Chen, {Y. P.} and D. VanEngelsdorp and H. Efrat and J. Pettis and D. Cox-Foster and Holmes, {E. C.} and T. Briese and Lipkin, {W. I.}",

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Palacios, G, Hui, J, Quan, PL, Kalkstein, A, Honkavuori, KS, Bussetti, AV, Conlan, S, Evans, J, Chen, YP, VanEngelsdorp, D, Efrat, H, Pettis, J, Cox-Foster, D, Holmes, EC, Briese, T & Lipkin, WI 2008, 'Genetic analysis of Israel acute paralysis virus: Distinct clusters are circulating in the United States', Journal of virology, vol. 82, no. 13, pp. 6209-6217. https://doi.org/10.1128/JVI.00251-08

TY - JOUR

T1 - Genetic analysis of Israel acute paralysis virus

T2 - Distinct clusters are circulating in the United States

AU - Palacios, G.

AU - Hui, J.

AU - Quan, P. L.

AU - Kalkstein, A.

AU - Honkavuori, K. S.

AU - Bussetti, A. V.

AU - Conlan, S.

AU - Evans, J.

AU - Chen, Y. P.

AU - VanEngelsdorp, D.

AU - Efrat, H.

AU - Pettis, J.

AU - Cox-Foster, D.

AU - Holmes, E. C.

AU - Briese, T.

AU - Lipkin, W. I.

PY - 2008/7

Y1 - 2008/7

N2 - Israel acute paralysis virus (IAPV) is associated with colony collapse disorder of honey bees. Nonetheless, its role in the pathogenesis of the disorder and its geographic distribution are unclear. Here, we report phylogenetic analysis of IAPV obtained from bees in the United States, Canada, Australia, and Israel and the establishment of diagnostic real-time PCR assays for IAPV detection. Our data indicate the existence of at least three distinct IAPV lineages, two of them circulating in the United States. Analysis of representatives from each proposed lineage suggested the possibility of recombination events and revealed differences in coding sequences that may have implications for virulence.

AB - Israel acute paralysis virus (IAPV) is associated with colony collapse disorder of honey bees. Nonetheless, its role in the pathogenesis of the disorder and its geographic distribution are unclear. Here, we report phylogenetic analysis of IAPV obtained from bees in the United States, Canada, Australia, and Israel and the establishment of diagnostic real-time PCR assays for IAPV detection. Our data indicate the existence of at least three distinct IAPV lineages, two of them circulating in the United States. Analysis of representatives from each proposed lineage suggested the possibility of recombination events and revealed differences in coding sequences that may have implications for virulence.

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Genetic analysis of Israel acute paralysis virus: Distinct clusters are circulating in the United States

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