Genetic Variation Shapes Murine Gut Microbiota via Immunity

Emily R. Davenport

doi:10.1016/j.it.2019.11.009

Genetic Variation Shapes Murine Gut Microbiota via Immunity

Emily R. Davenport

Research output: Contribution to journal › Short survey › peer-review

7 Scopus citations

Abstract

Host genetics influence gut microbiome composition. However, determining the specific physiological mechanisms and microbes affected has been difficult due to ‘cage’ and ‘legacy’ effects in model systems. Recently, Khan et al. cleverly colonized ex-germ-free mice to demonstrate that immune genes regulate select bacterial lineages in the mouse gut.

Original language	English (US)
Pages (from-to)	1-3
Number of pages	3
Journal	Trends in Immunology
Volume	41
Issue number	1
DOIs	https://doi.org/10.1016/j.it.2019.11.009
State	Published - Jan 2020

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Immunology

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10.1016/j.it.2019.11.009

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title = "Genetic Variation Shapes Murine Gut Microbiota via Immunity",

abstract = "Host genetics influence gut microbiome composition. However, determining the specific physiological mechanisms and microbes affected has been difficult due to {\textquoteleft}cage{\textquoteright} and {\textquoteleft}legacy{\textquoteright} effects in model systems. Recently, Khan et al. cleverly colonized ex-germ-free mice to demonstrate that immune genes regulate select bacterial lineages in the mouse gut.",

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Genetic Variation Shapes Murine Gut Microbiota via Immunity

Abstract

All Science Journal Classification (ASJC) codes

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