TY - JOUR
T1 - Genomic encyclopedia of type strains of the genus Bifidobacterium
AU - Milani, Christian
AU - Lugli, Gabriele Andrea
AU - Duranti, Sabrina
AU - Turroni, Francesca
AU - Bottacini, Francesca
AU - Mangifesta, Marta
AU - Sanchez, Borja
AU - Viappiani, Alice
AU - Mancabelli, Leonardo
AU - Taminiau, Bernard
AU - Delcenserie, Véronique
AU - Barrangou, Rodolphe
AU - Margolles, Abelardo
AU - Sinderen, Douwe van
AU - Ventura, Marco
N1 - Publisher Copyright:
© 2014, American Society for Microbiology.
PY - 2014
Y1 - 2014
N2 - Bifidobacteria represent one of the dominant microbial groups that are present in the gut of various animals, being particularly prevalent during the suckling stage of life of humans and other mammals. However, the overall genome structure of this group of microorganisms remains largely unexplored. Here, we sequenced the genomes of 42 representative (sub)species across the Bifidobacterium genus and used this information to explore the overall genetic picture of this bacterial group. Furthermore, the genomic data described here were used to reconstruct the evolutionary development of the Bifidobacterium genus. This reconstruction suggests that its evolution was substantially influenced by genetic adaptations to obtain access to glycans, thereby representing a common and potent evolutionary force in shaping bifidobacterial genomes.
AB - Bifidobacteria represent one of the dominant microbial groups that are present in the gut of various animals, being particularly prevalent during the suckling stage of life of humans and other mammals. However, the overall genome structure of this group of microorganisms remains largely unexplored. Here, we sequenced the genomes of 42 representative (sub)species across the Bifidobacterium genus and used this information to explore the overall genetic picture of this bacterial group. Furthermore, the genomic data described here were used to reconstruct the evolutionary development of the Bifidobacterium genus. This reconstruction suggests that its evolution was substantially influenced by genetic adaptations to obtain access to glycans, thereby representing a common and potent evolutionary force in shaping bifidobacterial genomes.
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U2 - 10.1128/AEM.02308-14
DO - 10.1128/AEM.02308-14
M3 - Article
C2 - 25085493
AN - SCOPUS:84907266451
SN - 0099-2240
VL - 80
SP - 6290
EP - 6302
JO - Applied and environmental microbiology
JF - Applied and environmental microbiology
IS - 20
ER -