Ginger supplement significantly reduced length of hospital stay in individuals with COVID-19

Yaqi Li, Dawei Yang, Xiwen Gao, Minjie Ju, Hao Fang, Zuoqin Yan, Huanru Qu, Yuanhao Zhang, Linshan Xie, Huifen Weng, Chunxue Bai, Yuanlin Song, Zhirong Sun, Wenye Geng, Xiang Gao

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Background: Evidence from previous studies has suggested that ginger extract exhibits the potential as an alternative treatment for Coronavirus disease 2019 (COVID-19). Here, we want to investigate whether ginger supplement improves the clinical manifestation of hospitalized COVID-19 individuals. Methods: A total of 227 hospitalized individuals with COVID-19 were randomized to either the control (n = 132) or intervention group (n = 95). The intervention group took ginger supplement orally at the dosage of 1.5 g twice daily, until they were discharged from the hospital. Both groups received the same standard of general medical care during hospitalization, and the length of stay was recorded and compared between groups. Results: Among all participants, a significant reduction in hospitalization time (the difference between the treatment and control groups was 2.4 d, 95% CI 1.6–3.2) was detected in response to the ginger supplement. This effect was more pronounced in men, participants aged 60 years or older, and participants with pre-existing medical conditions, relative to their counterparts (P-interactions < 0.05 for all). Conclusion: Ginger supplement significantly shortened the length of stay of hospitalized individuals with COVID-19. Trial registration: The trial was registered on the Chinese Clinical Trial Registry (ChiCTR2200059824).

Original languageEnglish (US)
Article number84
JournalNutrition and Metabolism
Issue number1
StatePublished - Dec 2022

All Science Journal Classification (ASJC) codes

  • Nutrition and Dietetics
  • Endocrinology, Diabetes and Metabolism
  • Medicine (miscellaneous)


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