Global deletion of BCATm increases expression of skeletal muscle genes associated with protein turnover

Keyphrases

• Skeletal muscle 100%
• BCATm 100%
• Muscle Genes 100%
• Protein Turnover 100%
• Knock-in Mouse Model 60%
• Protein Synthesis 40%
• Wild Mice 40%
• Protein Degradation 40%
• Leucine 40%
• Nutrient Sensing 40%
• Carbohydrate Metabolism 20%
• Adaptation 20%
• Mammalian Target of Rapamycin (mTOR) 20%
• P70S6K 20%
• Gastrocnemius 20%
• Cell Death 20%
• Muscle Fiber 20%
• Apoptosis 20%
• Lipid Signaling 20%
• EIF2 20%
• Bioinformatics Analysis 20%
• Metabolic 20%
• Body Size 20%
• Ubiquitin 20%
• Plasma Insulin 20%
• Transcriptome 20%
• Branched-chain Amino Acids 20%
• Branched-chain Aminotransferase 20%
• Ribosomal Protein 20%
• Plasma Lipids 20%
• Muscular Dystrophy 20%
• Insulin Signaling Pathway 20%
• Oxidative Metabolism 20%
• Elevated Protein 20%
• Atrophy 20%
• Myopathy 20%
• Exercise Intolerance 20%
• Glycemia 20%
• Reduced Body 20%
• Fatty Acid Chain 20%
• Muscle Degeneration 20%

Biochemistry, Genetics and Molecular Biology

• Knockout Mouse 100%
• Skeletal Muscle 100%
• Protein Degradation 100%
• RNA Sequence 66%
• Mouse 66%
• Protein Biosynthesis 66%
• Protein Catabolism 66%
• Wild Type Mouse 66%
• Leucine 66%
• Amino Acids 33%
• Metabolite 33%
• Signal Transduction 33%
• Ubiquitin 33%
• Ribosomal Protein 33%
• Transcriptome 33%
• Cell Death 33%
• Eukaryotic Initiation Factor 33%
• Lipid Signaling 33%
• Body Size 33%
• Blood Lipids 33%
• Transaminase 33%
• Insulin Signaling 33%
• Glucose Blood Level 33%
• Insulin Blood Level 33%
• Aerobic Metabolism 33%
• Mammalian Target of Rapamycin Complex 2 33%