Glucose transporter Glut 5 expression in microglial cells

Jennifer Payne; Fran Maher; Ian Simpson; Linda Mattice; Peter Davies

doi:10.1002/(SICI)1098-1136(199711)21:3<327::AID-GLIA7>3.0.CO;2-1

Glucose transporter Glut 5 expression in microglial cells

Jennifer Payne, Fran Maher, Ian Simpson, Linda Mattice, Peter Davies

Department of Neural and Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

109 Scopus citations

Abstract

Glut 5 is a member of a family of facilitative glucose transporter proteins that are involved in the transportation of glucose and/or fructose across plasma membranes. Glut 5 is one of three isoforms expressed in brain. Using immunocytochemical and immunoblotting techniques in formalin fixed tissue, we have shown that Glut 5 is exclusively expressed in microglial cells of the human and rat brain. Our data demonstrate that unlike other microglial markers, Glut 5 can be used as a microglial marker in formalin fixed tissue.

Original language	English (US)
Pages (from-to)	327-331
Number of pages	5
Journal	Glia
Volume	21
Issue number	3
DOIs	https://doi.org/10.1002/(SICI)1098-1136(199711)21:3<327::AID-GLIA7>3.0.CO;2-1
State	Published - Nov 1997

All Science Journal Classification (ASJC) codes

Neurology
Cellular and Molecular Neuroscience

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10.1002/(SICI)1098-1136(199711)21:3<327::AID-GLIA7>3.0.CO;2-1

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AU - Simpson, Ian

AU - Mattice, Linda

AU - Davies, Peter

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AB - Glut 5 is a member of a family of facilitative glucose transporter proteins that are involved in the transportation of glucose and/or fructose across plasma membranes. Glut 5 is one of three isoforms expressed in brain. Using immunocytochemical and immunoblotting techniques in formalin fixed tissue, we have shown that Glut 5 is exclusively expressed in microglial cells of the human and rat brain. Our data demonstrate that unlike other microglial markers, Glut 5 can be used as a microglial marker in formalin fixed tissue.

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Glucose transporter Glut 5 expression in microglial cells

Abstract

All Science Journal Classification (ASJC) codes

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