@inproceedings{8299c59b60214961b4e509efbd16c2f3,
title = "Grammatical evolution of neural networks for discovering epistasis among quantitative trait loci",
abstract = "Growing interest and burgeoning technology for discovering genetic mechanisms that influence disease processes have ushered in a flood of genetic association studies over the last decade, yet little heritability in highly studied complex traits has been explained by genetic variation. Non-additive gene-gene interactions, which are not often explored, are thought to be one source of this {"}missing{"} heritability. Here we present our assessment of the performance of grammatical evolution to evolve neural networks (GENN) for discovering gene-gene interactions which contribute to a quantitative heritable trait. We present several modifications to the GENN procedure which result in modest improvements in performance.",
author = "Turner, {Stephen D.} and Dudek, {Scott M.} and Ritchie, {Marylyn D.}",
note = "Copyright: Copyright 2021 Elsevier B.V., All rights reserved.; 8th European Conference on Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics, EvoBIO 2010 ; Conference date: 07-04-2010 Through 09-04-2010",
year = "2010",
doi = "10.1007/978-3-642-12211-8_8",
language = "English (US)",
isbn = "3642122108",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
publisher = "Springer Verlag",
pages = "86--97",
booktitle = "Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics - 8th European Conference, EvoBIO 2010, Proceedings",
address = "Germany",
}