TY - JOUR
T1 - Growth Factors and Wound Healing in the Hamster
AU - LEITZEL, KIM
AU - CANO, CHERYL
AU - MARKS, JAMES G.
AU - LIPTON, ALLAN
PY - 1985/6
Y1 - 1985/6
N2 - We have investigated the effect of topically applied mitogenic preparations on the healing of full‐thickness skin wounds in the Syrian hamster. In an attempt to accelerate the healing process, dexamethasone and insulin, platelet‐derived growth factor, fibroblast growth factor, thrombin, defined medium F for fibroblasts, liver cell supernatant, epidermal growth factor, and colostrum were applied to the wounds. These mitogens had no significant influence on the rate of wound contraction or on the time to complete healing in full‐thickness, noncompromised skin wounds in this animal model. 1985 American Society for Dermatologic Surgery, Inc.
AB - We have investigated the effect of topically applied mitogenic preparations on the healing of full‐thickness skin wounds in the Syrian hamster. In an attempt to accelerate the healing process, dexamethasone and insulin, platelet‐derived growth factor, fibroblast growth factor, thrombin, defined medium F for fibroblasts, liver cell supernatant, epidermal growth factor, and colostrum were applied to the wounds. These mitogens had no significant influence on the rate of wound contraction or on the time to complete healing in full‐thickness, noncompromised skin wounds in this animal model. 1985 American Society for Dermatologic Surgery, Inc.
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U2 - 10.1111/j.1524-4725.1985.tb01906.x
DO - 10.1111/j.1524-4725.1985.tb01906.x
M3 - Article
C2 - 3891806
AN - SCOPUS:0022413141
SN - 0148-0812
VL - 11
SP - 617
EP - 627
JO - The Journal of Dermatologic Surgery and Oncology
JF - The Journal of Dermatologic Surgery and Oncology
IS - 6
ER -