GTPase signaling: Bridging the GAP between ARF and Rho

Lorraine C. Santy, James E. Casanova

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations


Membrane traffic and actin cytoskeleton dynamics are intimately linked, and GTPases of the Rho and ARF families may work together to regulate both. Recent studies have identified a family of GTPase activating proteins (GAPs) that contain both ARF-GAP and Rho-GAP domains, providing the first direct link between these two signaling pathways.

Original languageEnglish (US)
Pages (from-to)R360-R362
JournalCurrent Biology
Issue number10
StatePublished - May 14 2002

All Science Journal Classification (ASJC) codes

  • General Biochemistry, Genetics and Molecular Biology
  • General Agricultural and Biological Sciences


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