GTPase signaling: Bridging the GAP between ARF and Rho

Lorraine C. Santy; James E. Casanova

doi:10.1016/S0960-9822(02)00860-6

GTPase signaling: Bridging the GAP between ARF and Rho

Lorraine C. Santy
, James E. Casanova

Research output: Contribution to journal › Review article › peer-review

27 Scopus citations

Abstract

Membrane traffic and actin cytoskeleton dynamics are intimately linked, and GTPases of the Rho and ARF families may work together to regulate both. Recent studies have identified a family of GTPase activating proteins (GAPs) that contain both ARF-GAP and Rho-GAP domains, providing the first direct link between these two signaling pathways.

Original language	English (US)
Pages (from-to)	R360-R362
Journal	Current Biology
Volume	12
Issue number	10
DOIs	https://doi.org/10.1016/S0960-9822(02)00860-6
State	Published - May 14 2002

All Science Journal Classification (ASJC) codes

General Biochemistry, Genetics and Molecular Biology
General Agricultural and Biological Sciences

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10.1016/S0960-9822(02)00860-6

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title = "GTPase signaling: Bridging the GAP between ARF and Rho",

abstract = "Membrane traffic and actin cytoskeleton dynamics are intimately linked, and GTPases of the Rho and ARF families may work together to regulate both. Recent studies have identified a family of GTPase activating proteins (GAPs) that contain both ARF-GAP and Rho-GAP domains, providing the first direct link between these two signaling pathways.",

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T1 - GTPase signaling

T2 - Bridging the GAP between ARF and Rho

AU - Santy, Lorraine C.

AU - Casanova, James E.

PY - 2002/5/14

Y1 - 2002/5/14

N2 - Membrane traffic and actin cytoskeleton dynamics are intimately linked, and GTPases of the Rho and ARF families may work together to regulate both. Recent studies have identified a family of GTPase activating proteins (GAPs) that contain both ARF-GAP and Rho-GAP domains, providing the first direct link between these two signaling pathways.

AB - Membrane traffic and actin cytoskeleton dynamics are intimately linked, and GTPases of the Rho and ARF families may work together to regulate both. Recent studies have identified a family of GTPase activating proteins (GAPs) that contain both ARF-GAP and Rho-GAP domains, providing the first direct link between these two signaling pathways.

UR - https://www.scopus.com/pages/publications/0037076462

UR - https://www.scopus.com/pages/publications/0037076462#tab=citedBy

U2 - 10.1016/S0960-9822(02)00860-6

DO - 10.1016/S0960-9822(02)00860-6

M3 - Review article

C2 - 12015138

AN - SCOPUS:0037076462

SN - 0960-9822

VL - 12

SP - R360-R362

JO - Current Biology

JF - Current Biology

IS - 10

ER -

GTPase signaling: Bridging the GAP between ARF and Rho

Abstract

All Science Journal Classification (ASJC) codes

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