Gustatory impairment in patients undergoing head and neck irradiation

Natasha Mirza; Mitchell Machtay; Pamela A. Devine; Andrea Troxel; Soo K. Abboud; Richard L. Doty

doi:10.1097/MLG.0b013e318155a276

Gustatory impairment in patients undergoing head and neck irradiation

Natasha Mirza, Mitchell Machtay, Pamela A. Devine, Andrea Troxel, Soo K. Abboud, Richard L. Doty

Research output: Contribution to journal › Article › peer-review

58 Scopus citations

Abstract

OBJECTIVES: To determine whether radiation alters taste function and structure. RESEARCH DESIGN: Prospective, longitudinal study. METHODOLOGY: Testing prior to starting radiation, and 2 weeks, 2 months, and 6 months after completing radiation. RESULTS: Relative to controls, patients had lower taste identification test scores for bitter, salty, and sour tastes. Sour taste also showed a significant group-by-time interaction (P = .03). Taste pores were decreased in the irradiated group, with a significant group-by-time interaction (P = .03). CONCLUSION: Head and neck cancer patients have decreased taste function, and radiation adversely affected sour taste and taste pores.

Original language	English (US)
Pages (from-to)	24-31
Number of pages	8
Journal	Laryngoscope
Volume	118
Issue number	1
DOIs	https://doi.org/10.1097/MLG.0b013e318155a276
State	Published - Jan 2008

All Science Journal Classification (ASJC) codes

Otorhinolaryngology

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10.1097/MLG.0b013e318155a276

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title = "Gustatory impairment in patients undergoing head and neck irradiation",

abstract = "OBJECTIVES: To determine whether radiation alters taste function and structure. RESEARCH DESIGN: Prospective, longitudinal study. METHODOLOGY: Testing prior to starting radiation, and 2 weeks, 2 months, and 6 months after completing radiation. RESULTS: Relative to controls, patients had lower taste identification test scores for bitter, salty, and sour tastes. Sour taste also showed a significant group-by-time interaction (P = .03). Taste pores were decreased in the irradiated group, with a significant group-by-time interaction (P = .03). CONCLUSION: Head and neck cancer patients have decreased taste function, and radiation adversely affected sour taste and taste pores.",

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doi = "10.1097/MLG.0b013e318155a276",

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T1 - Gustatory impairment in patients undergoing head and neck irradiation

AU - Mirza, Natasha

AU - Machtay, Mitchell

AU - Devine, Pamela A.

AU - Troxel, Andrea

AU - Abboud, Soo K.

AU - Doty, Richard L.

PY - 2008/1

Y1 - 2008/1

N2 - OBJECTIVES: To determine whether radiation alters taste function and structure. RESEARCH DESIGN: Prospective, longitudinal study. METHODOLOGY: Testing prior to starting radiation, and 2 weeks, 2 months, and 6 months after completing radiation. RESULTS: Relative to controls, patients had lower taste identification test scores for bitter, salty, and sour tastes. Sour taste also showed a significant group-by-time interaction (P = .03). Taste pores were decreased in the irradiated group, with a significant group-by-time interaction (P = .03). CONCLUSION: Head and neck cancer patients have decreased taste function, and radiation adversely affected sour taste and taste pores.

AB - OBJECTIVES: To determine whether radiation alters taste function and structure. RESEARCH DESIGN: Prospective, longitudinal study. METHODOLOGY: Testing prior to starting radiation, and 2 weeks, 2 months, and 6 months after completing radiation. RESULTS: Relative to controls, patients had lower taste identification test scores for bitter, salty, and sour tastes. Sour taste also showed a significant group-by-time interaction (P = .03). Taste pores were decreased in the irradiated group, with a significant group-by-time interaction (P = .03). CONCLUSION: Head and neck cancer patients have decreased taste function, and radiation adversely affected sour taste and taste pores.

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Gustatory impairment in patients undergoing head and neck irradiation

Abstract

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