H‐2 haplotypes carrying identical D but different L alleles

F. Figueroa; S. Tewarson; P. Walden; Z. A. Nagy; J. Klein

doi:10.1111/j.1399-0039.1983.tb00367.x

H‐2 haplotypes carrying identical D but different L alleles

F. Figueroa, S. Tewarson, P. Walden, Z. A. Nagy, J. Klein

Biology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The B10.SAA48 congenic line was derived by transferring the H‐2 haplotype of a wild mouse onto the background of the inbred strain C57BL/10Sn (abbreviated as B10). The line carries the D^w3 allele in combination with an L allele different from that present in other D^w3 strains. One possible explanation of this finding is that crossing over occurred between the D and L loci. The determinants H‐2.m64 and H‐2.m65 represent an inclusion doublet in which the latter never occurs without the former. Typing of B10.W lines with L^d‐specific CTLs reveals the absence of this allele in all the lines, including those carrying an allele serologically similar to L^d.

Original language	English (US)
Pages (from-to)	24-30
Number of pages	7
Journal	Tissue Antigens
Volume	21
Issue number	1
DOIs	https://doi.org/10.1111/j.1399-0039.1983.tb00367.x
State	Published - Jan 1983

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Immunology
Biochemistry
Genetics

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10.1111/j.1399-0039.1983.tb00367.x

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title = "H‐2 haplotypes carrying identical D but different L alleles",

abstract = "The B10.SAA48 congenic line was derived by transferring the H‐2 haplotype of a wild mouse onto the background of the inbred strain C57BL/10Sn (abbreviated as B10). The line carries the Dw3 allele in combination with an L allele different from that present in other Dw3 strains. One possible explanation of this finding is that crossing over occurred between the D and L loci. The determinants H‐2.m64 and H‐2.m65 represent an inclusion doublet in which the latter never occurs without the former. Typing of B10.W lines with Ld‐specific CTLs reveals the absence of this allele in all the lines, including those carrying an allele serologically similar to Ld.",

author = "F. Figueroa and S. Tewarson and P. Walden and Nagy, {Z. A.} and J. Klein",

year = "1983",

month = jan,

doi = "10.1111/j.1399-0039.1983.tb00367.x",

language = "English (US)",

volume = "21",

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T1 - H‐2 haplotypes carrying identical D but different L alleles

AU - Figueroa, F.

AU - Tewarson, S.

AU - Walden, P.

AU - Nagy, Z. A.

AU - Klein, J.

PY - 1983/1

Y1 - 1983/1

N2 - The B10.SAA48 congenic line was derived by transferring the H‐2 haplotype of a wild mouse onto the background of the inbred strain C57BL/10Sn (abbreviated as B10). The line carries the Dw3 allele in combination with an L allele different from that present in other Dw3 strains. One possible explanation of this finding is that crossing over occurred between the D and L loci. The determinants H‐2.m64 and H‐2.m65 represent an inclusion doublet in which the latter never occurs without the former. Typing of B10.W lines with Ld‐specific CTLs reveals the absence of this allele in all the lines, including those carrying an allele serologically similar to Ld.

AB - The B10.SAA48 congenic line was derived by transferring the H‐2 haplotype of a wild mouse onto the background of the inbred strain C57BL/10Sn (abbreviated as B10). The line carries the Dw3 allele in combination with an L allele different from that present in other Dw3 strains. One possible explanation of this finding is that crossing over occurred between the D and L loci. The determinants H‐2.m64 and H‐2.m65 represent an inclusion doublet in which the latter never occurs without the former. Typing of B10.W lines with Ld‐specific CTLs reveals the absence of this allele in all the lines, including those carrying an allele serologically similar to Ld.

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H‐2 haplotypes carrying identical D but different L alleles

Abstract

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