Abstract
There are many regulated steps in the assembly of a transcription preinitiation complex (PIC). In this issue of Molecular Cell, Black et al. (2006) reveal a catalytic switch mechanism in which autoacetylation of the HAT p300 triggers its dissociation from a promoter in a manner that is coupled to TFIID association.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 776-777 |
| Number of pages | 2 |
| Journal | Molecular cell |
| Volume | 23 |
| Issue number | 6 |
| DOIs | |
| State | Published - Sep 15 2006 |
All Science Journal Classification (ASJC) codes
- Molecular Biology
- Cell Biology