TY - JOUR
T1 - Health-related quality of life one year after surgical treatment of the type I chronic aortic dissection
AU - Kamenskaya, Oksana
AU - Klinkova, Asya
AU - Loginova, Irina
AU - Chernyavskiy, Alexander
AU - Sirota, Dmitry
AU - Lomivorotov, Vladimir V.
AU - Karaskov, Alexander
N1 - Funding Information:
This work was supported by a Russian Science Foundation grant (Nº17-75-30009). The funding source had no involvement in the development of the research project, in the collection, analysis and interpretation of data, and in the decision to submit an article for publication.
Publisher Copyright:
© 2018 EDIZIONI MINERVA MEDICA.
PY - 2019/2
Y1 - 2019/2
N2 - Background: The purpose of our study was to assess the health-related quality of life (HRQoL) in patients with type I chronic aortic dissection before and one year after prosthetics of the aorta, and to test the hypothesis that long-term postoperative parameters of HRQoL are affected by clinical determinants related to the underlying disease, intraoperative characteristics, and complications of the early postoperative period. Methods: This prospective cohort study included 82 patients with type I chronic aortic dissection. HRQoL parameters were examined using the Short-Form 36 Health Survey Questionnaire before and one year after surgery. Results: Patients with aortic dissection one year after surgery demonstrated an improvement in many HRQoL parameters, including two summary measures of the questionnaire — Physical component summary (PCS) and Mental component summary (MCS). A lower level of PCS and MCS at the preoperative stage significantly predicted lower values of these indices for a long time after aortic prosthetics. The neurological complications in the early postoperative period were the factor affecting the MCS after surgery. Moreover, the neurological complications and the presence of coronary artery disease increased the risk of the adverse outcomes, including aortic related death and significant decrease of MCS or aortic related death and significant decrease of PCS one year after the operation, respectively. Conclusions: Surgical treatment in patients with type I chronic aortic dissection leads to an increase of many HRQoL parameters. Factors affecting MCS and PCS one year after surgery included the neurological complications and lower level of the MCS and PCS at the preoperative stage. Furthermore, the neurological complications and the presence of coronary artery disease increased the risk of the combined endpoints — aortic related death and significant decrease of MCS or aortic related death and significant decrease of PCS one year after the operation, respectively.
AB - Background: The purpose of our study was to assess the health-related quality of life (HRQoL) in patients with type I chronic aortic dissection before and one year after prosthetics of the aorta, and to test the hypothesis that long-term postoperative parameters of HRQoL are affected by clinical determinants related to the underlying disease, intraoperative characteristics, and complications of the early postoperative period. Methods: This prospective cohort study included 82 patients with type I chronic aortic dissection. HRQoL parameters were examined using the Short-Form 36 Health Survey Questionnaire before and one year after surgery. Results: Patients with aortic dissection one year after surgery demonstrated an improvement in many HRQoL parameters, including two summary measures of the questionnaire — Physical component summary (PCS) and Mental component summary (MCS). A lower level of PCS and MCS at the preoperative stage significantly predicted lower values of these indices for a long time after aortic prosthetics. The neurological complications in the early postoperative period were the factor affecting the MCS after surgery. Moreover, the neurological complications and the presence of coronary artery disease increased the risk of the adverse outcomes, including aortic related death and significant decrease of MCS or aortic related death and significant decrease of PCS one year after the operation, respectively. Conclusions: Surgical treatment in patients with type I chronic aortic dissection leads to an increase of many HRQoL parameters. Factors affecting MCS and PCS one year after surgery included the neurological complications and lower level of the MCS and PCS at the preoperative stage. Furthermore, the neurological complications and the presence of coronary artery disease increased the risk of the combined endpoints — aortic related death and significant decrease of MCS or aortic related death and significant decrease of PCS one year after the operation, respectively.
UR - https://www.scopus.com/pages/publications/85062818560
UR - https://www.scopus.com/pages/publications/85062818560#tab=citedBy
U2 - 10.23736/S0392-9590.18.04009-9
DO - 10.23736/S0392-9590.18.04009-9
M3 - Article
C2 - 30860340
AN - SCOPUS:85062818560
SN - 0392-9590
VL - 38
SP - 46
EP - 53
JO - International Angiology
JF - International Angiology
IS - 1
ER -