Heat-targeted drug delivery: A promising approach for organsparing treatment of bladder cancer

Alireza Aminsharifi; Steven C. Brousell; Andrew Chang; Juan León; Brant A. Inman

Heat-targeted drug delivery: A promising approach for organsparing treatment of bladder cancer

Alireza Aminsharifi, Steven C. Brousell, Andrew Chang, Juan León, Brant A. Inman

Research output: Contribution to journal › Article › peer-review

Abstract

Disease recurrence and progression remain as significant challenges for the management of non-muscle invasive bladder cancer (NMIBC). In recent years, novel drugs and delivery systems have been investigated as strategies to reduce recurrence, progression and mortality. In this review, we focus on the role of intravesical hyperthermic chemotherapy and discuss a novel approach involving a heat-activated drug delivery system (ThermoDox) that enables local accumulation of systemic chemotherapy.

Original language	English (US)
Pages (from-to)	447-452
Number of pages	6
Journal	Archivos Espanoles de Urologia
Volume	71
Issue number	4
State	Published - May 2018

All Science Journal Classification (ASJC) codes

Urology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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abstract = "Disease recurrence and progression remain as significant challenges for the management of non-muscle invasive bladder cancer (NMIBC). In recent years, novel drugs and delivery systems have been investigated as strategies to reduce recurrence, progression and mortality. In this review, we focus on the role of intravesical hyperthermic chemotherapy and discuss a novel approach involving a heat-activated drug delivery system (ThermoDox) that enables local accumulation of systemic chemotherapy.",

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AU - Aminsharifi, Alireza

AU - Brousell, Steven C.

AU - Chang, Andrew

AU - León, Juan

AU - Inman, Brant A.

PY - 2018/5

Y1 - 2018/5

N2 - Disease recurrence and progression remain as significant challenges for the management of non-muscle invasive bladder cancer (NMIBC). In recent years, novel drugs and delivery systems have been investigated as strategies to reduce recurrence, progression and mortality. In this review, we focus on the role of intravesical hyperthermic chemotherapy and discuss a novel approach involving a heat-activated drug delivery system (ThermoDox) that enables local accumulation of systemic chemotherapy.

AB - Disease recurrence and progression remain as significant challenges for the management of non-muscle invasive bladder cancer (NMIBC). In recent years, novel drugs and delivery systems have been investigated as strategies to reduce recurrence, progression and mortality. In this review, we focus on the role of intravesical hyperthermic chemotherapy and discuss a novel approach involving a heat-activated drug delivery system (ThermoDox) that enables local accumulation of systemic chemotherapy.

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ER -

Heat-targeted drug delivery: A promising approach for organsparing treatment of bladder cancer

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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