Heterocyclic compounds. VI. Synthesis of poly nuclear thienopyrimidine derivatives

M. S. Manhas, S. G. Amin

Research output: Contribution to journalComment/debatepeer-review

12 Scopus citations


Quinazoline derivatives have received great interest because of their potential biological activity. This communication describes a facile method for the synthesis of substituted thiophenopyrimidones. 2‐Amino‐3‐earbethoxy‐4,5‐tetramethylenethiophene on heating with substituted imidoyl‐chlorides, iminoethers, iminothioethers or thioamides affords thiophenopyrimidones. By using this method a number of such compounds of varying complexity were synthesized which are otherwise not so easily accessible.

Original languageEnglish (US)
Pages (from-to)903-906
Number of pages4
JournalJournal of Heterocyclic Chemistry
Issue number4
StatePublished - Aug 1976

All Science Journal Classification (ASJC) codes

  • Organic Chemistry


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