TY - JOUR
T1 - Heterogeneity in DSM-5 Symptom Criteria
T2 - Phenotypes of Alcohol Use Disorder in a Sample Seeking Alcohol Treatment
AU - Zhao, Junru
AU - Linn, Braden
AU - Bradizza, Clara
AU - Lucke, Joseph
AU - Ruszczyk, Melanie
AU - Stasiewicz, Paul
N1 - Publisher Copyright:
© 2021 The Author(s). Medical Council on Alcohol and Oxford University Press. All rights reserved.
PY - 2021/11/1
Y1 - 2021/11/1
N2 - Aims: This study sought to identify phenotypic variations among individuals with alcohol use disorder (AUD) that may, in part, help improve the effectiveness of existing AUD interventions. Methods: Latent class analysis was conducted to examine the potential heterogeneity of AUD in a sample (N = 220; Mage = 51.19 years, standard deviation = 9.94; 37.7% female) of treatment-seeking participants diagnosed with AUD using DSM-5 criteria. Results and Conclusions: Three distinct patterns of responses to the 11 DSM-5 AUD symptoms emerged: Class 1 (n = 114, 51.8%), Class 2 (n = 78, 35.5%) and Class 3 (n = 28, 12.7%). The identified profiles were further differentiated by demographics, alcohol-related constructs, individual difference characteristics and diagnostic and treatment variables. The findings have implications for refining AUD assessment as well as optimizing personalized treatment.
AB - Aims: This study sought to identify phenotypic variations among individuals with alcohol use disorder (AUD) that may, in part, help improve the effectiveness of existing AUD interventions. Methods: Latent class analysis was conducted to examine the potential heterogeneity of AUD in a sample (N = 220; Mage = 51.19 years, standard deviation = 9.94; 37.7% female) of treatment-seeking participants diagnosed with AUD using DSM-5 criteria. Results and Conclusions: Three distinct patterns of responses to the 11 DSM-5 AUD symptoms emerged: Class 1 (n = 114, 51.8%), Class 2 (n = 78, 35.5%) and Class 3 (n = 28, 12.7%). The identified profiles were further differentiated by demographics, alcohol-related constructs, individual difference characteristics and diagnostic and treatment variables. The findings have implications for refining AUD assessment as well as optimizing personalized treatment.
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U2 - 10.1093/alcalc/agaa138
DO - 10.1093/alcalc/agaa138
M3 - Article
C2 - 33420777
AN - SCOPUS:85119359968
SN - 0735-0414
VL - 56
SP - 660
EP - 668
JO - Alcohol and Alcoholism
JF - Alcohol and Alcoholism
IS - 6
ER -