Heterogeneous Recurrence Analysis of Disease-Altered Spatiotemporal Patterns in Multi-Channel Cardiac Signals

Ruimin Chen, Farhad Imani, Hui Yang

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Heart diseases alter the rhythmic behaviors of cardiac electrical activity. Recent advances in sensing technology bring the ease to acquire space-time electrical activity of the heart such as vectorcardiogram (VCG) signals. Recurrence analysis of successive heartbeats is conducive to detect the disease-altered cardiac activities. However, conventional recurrence analysis is more concerned about homogeneous recurrences, and overlook heterogeneous types of recurrence variations in VCG signals (i.e., in terms of state properties and transition dynamics). This paper presents a new framework of heterogeneous recurrence analysis for the characterization and modeling of disease-altered spatiotemporal patterns in multi-channel cardiac signals. Experimental results show that the proposed approach yields an accuracy of 96.9%, a sensitivity of 95.0%, and a specificity of 98.7% for the identification of myocardial infarctions. The proposed method of heterogeneous recurrence analysis shows strong potential to be further extended for the analysis of other physiological signals such as electroencephalogram (EEG) and electromyography (EMG) signals towards medical decision making.

Original languageEnglish (US)
Article number8894471
Pages (from-to)1619-1631
Number of pages13
JournalIEEE Journal of Biomedical and Health Informatics
Issue number6
StatePublished - Jun 2020

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Computer Science Applications
  • Electrical and Electronic Engineering
  • Health Information Management


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